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Steady-state expression of self-regulated genes

Fournier, T. ; Gabriel, J.P. ; Mazza, C. ; Pasquier, J. ; Galbete, J.L. ; Mermod, N.

In: Bioinformatics, 2007, vol. 23, no. 23, p. 3185-3192

Steady-state expression of self-regulated genes

Fournier, Thomas ; Gabriel, Jean-Pierre ; Mazza, Christian ; Pasquier, Jérôme ; Galbete, J.L. ; Mermod, Nicolas

In: Bioinformatics, 2007, vol. 23, no. 23, p. 3185-3192

Motivation: Regulatory gene networks contain generic modules such as feedback loops that are essential for the regulation of many biological functions. The study of the stochastic mechanisms of gene regulation is instrumental for the understanding of how cells maintain their expression at levels commensurate with their biological role, as well as to engineer gene expression switches of...