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FRI-2 carbapenemase-producing Enterobacter cloacae complex in the UK

Meunier, Danièle ; Findlay, Jacqueline ; Doumith, Michel ; Godoy, Daniel ; Perry, Claire ; Pike, Rachel ; Gronthoud, Firza ; Shryane, Theresa ; Poirel, Laurent ; Welfare, William ; Woodford, Neil ; Hopkins, Katie L.

In: Journal of Antimicrobial Chemotherapy, 2017, vol. 72, no. 9, p. 2478–2482

Objectives: Detection of rarer carbapenemases is challenging, as it requires molecular assays with comprehensive coverage or the use of phenotypic methods for the detection of carbapenemase activity. We describe a new class A carbapenemase, FRI-2, in an Enterobacter cloacae complex isolate following implementation of an in- house multiplex PCR for the detection of ‘rare’ class A...