In: Brain, 2014, vol. 137, no. 5, p. 1454-1469
|
In: Acta Neuropathologica, 2011, vol. 122, no. 5, p. 601-614
|
In: Frontiers in immunology, 2019, vol. 10, p. 711
Breakdown of the blood-brain barrier (BBB) and increased immune cell trafficking into the central nervous system (CNS) are hallmarks of the pathogenesis of multiple sclerosis (MS). Platelet endothelial cell adhesion molecule-1 (PECAM-1; CD31) is expressed on cells of the vascular compartment and regulates vascular integrity and immune cell trafficking. Involvement of PECAM-1 in MS pathogenesis...
|