Université de Fribourg

Contrast-induced nephropathy in invasive cardiology: incidence, pathophysiology, diagnosis, prevention and prognosis

Perrin, Tilman ; Descombes, Eric ; Cook, Stéphane

In: Swiss Medical Weekly, 2012, vol. 142, p. w13608

Contrast-induced nephropathy (CIN) is an acute renal injury due to the renal toxicity of iodinated contrast media. It is classically defined as a relative (≥25%) or absolute (≥0.5 mg/dl; 44 μmol/l) increase in serum creatinine from baseline value. CIN accounts for 10 to 15% of hospital-acquired acute renal failure and may rarely lead to irreversible renal function loss. Following...