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Lab mice in the field: unorthodox daily activity and effects of a dysfunctional circadian clock allele

Spoelstra, Kamiel ; Albrecht, Urs ; Schmutz, Isabelle ; Daan, Moritz ; Daan, Berte ; Rienks, Froukje ; Poletaeva, Inga ; Dell'Omo, Giacomo ; Vyssotski, Alexei ; Lipp, Hans-Peter

In: Journal of Biological Rhytms, 2011, vol. 26, no. 2, p. 118-129

Daily patterns of animal behavior are potentially of vast functional importance. Fitness benefits have been identified in nature by the association between individual timing and survival or by the fate of individuals after experimental deletion of their circadian pacemaker. The recent advances in unraveling the molecular basis of circadian timing enable new approaches to natural selection on...