Université de Fribourg

Admixture mapping in interspecific Populus hybrids identifies classes of genomic architectures for phytochemical, morphological and growth traits

Bresadola, Luisa ; Caseys, Céline ; Castiglione, Stefano ; Buerkle, C. Alex ; Wegmann, Daniel ; Lexer, Christian

In: New Phytologist, 2019, vol. 223, no. 4, p. 2076–2089

The genomic architecture of functionally important traits is key to understanding the maintenance of reproductive barriers and trait differences when divergent populations or species hybridize. We conducted a genome-wide association study (GWAS) to study trait architecture in natural hybrids of two ecologically divergent Populus species. We genotyped 472 seedlings from a natural hybrid zone...

Université de Fribourg

Genome-wide patterns of differentiation and spatially varying selection between postglacial recolonization lineages of Populus alba (Salicaceae), a widespread forest tree

Stölting, Kai N. ; Paris, Margot ; Meier, Cécile ; Heinze, Berthold ; Castiglione, Stefano ; Bartha, Denes ; Lexer, Christian

In: New Phytologist, 2015, vol. 207, no. 3, p. 723–734

Studying the divergence continuum in plants is relevant to fundamental and applied biology because of the potential to reveal functionally important genetic variation. In this context, whole-genome sequencing (WGS) provides the necessary rigour for uncovering footprints of selection. We resequenced populations of two divergent phylogeographic lineages of Populus alba (n = 48), thoroughly...

Université de Fribourg

Genomic scan for single nucleotide polymorphisms reveals patterns of divergence and gene flow between ecologically divergent species

Stölting, Kai N. ; Nipper, Rick ; Lindtke, Dorothea ; Caseys, Celine ; Waeber, Stephan ; Castiglione, Stefano ; Lexer, Christian

In: Molecular Ecology, 2013, vol. 22, no. 3, p. 842–855

Recent advances in population genomics have triggered great interest in the genomic landscape of divergence in taxa with ‘porous’ species boundaries. One important obstable of previous studies of this topic was the low genomic coverage achieved. This issue can now be overcome by the use of ‘next generation’ or short-read DNA-sequencing approaches capable of assaying many thousands of...

Université de Fribourg

Recombinant hybrids retain heterozygosity at many loci: new insights into the genomics of reproductive isolation in Populus

Lindtke, Dorothea ; Buerkle, C. Alex ; Barbará, Thelma ; Heinze, Berthold ; Castiglione, Stefano ; Bartha, Denes ; Lexer, Christian

In: Molecular Ecology, 2012, p. -

The maintenance of species barriers in the face of gene flow is often thought to result from strong selection against intermediate genotypes, thereby preserving genetic differentiation. Most speciation genomic studies thus aim to identify exceptionally divergent loci between populations, but divergence will be affected by many processes other than reproductive isolation (RI) and speciation....

Université de Fribourg

Genomic admixture analysis in european Populus spp. reveals unexpected patterns of reproductive isolation and mating

Lexer, Christian ; Joseph, Jeffrey A. ; Loo, Marcela van ; Barbará, Thelma ; Heinze, Berthold ; Bartha, Denes ; Castiglione, Stefano ; Fay, Michael F. ; Buerkle, C. Alex

In: Genetics, 2010, vol. 186, p. 699–712

Admixture between genetically divergent populations facilitates genomic studies of the mechanisms involved in adaptation, reproductive isolation and speciation, including mapping of the loci involved in these phenomena. Little is known about how pre- and postzygotic barriers will affect the prospects of 'admixture mapping' in wild species. We have studied 93 mapped genetic markers...