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Role of CXCL13 and CCL20 in the recruitment of B cells to inflammatory foci in chronic arthritis

Armas-González, Estefanía ; Domínguez-Luis, María Jesús ; Díaz-Martín, Ana ; Arce-Franco, Mayte ; Castro-Hernández, Javier ; Danelon, Gabriela ; Hernández-Hernández, Vanesa ; Bustabad-Reyes, Sagrario ; Cantabrana, Alberto ; Uguccioni ; Díaz-González, Federico

In: Arthritis research & therapy, 2018, vol. 20, p. 114

Background: B cells exert their pathogenic action in rheumatoid arthritis (RA) locally in the synovium. This study was undertaken to elucidate the chemokines responsible for the recruitment of B cells in the inflamed synovium, taking into account that the rich chemokine milieu present in the synovial tissue can fine-tune modulate discrete chemokine receptors. Methods: Expression levels of...