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Single cell transcriptome atlas of the Drosophila larval brain

Brunet Avalos, Clarisse ; Maier, G. Larisa ; Bruggmann, Rémy ; Sprecher, Simon G.

In: eLife, 2019, vol. 8, p. e50354

Cell diversity of the brain and how it is affected by starvation, remains largely unknown. Here, we introduce a single cell transcriptome atlas of the entire Drosophila first instar larval brain. We first assigned cell-type identity based on known marker genes, distinguishing five major groups: neural progenitors, differentiated neurons, glia, undifferentiated neurons and non-neural cells....