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Influence of anti-Nogo-A antibody treatment on the reorganization of callosal connectivity of the premotor cortical areas following unilateral lesion of primary motor cortex (M1) in adult macaque monkeys

Hamadjida, Adjia ; Wyss, Alexander ; Mir, Anis ; Schwab, Martin ; Belhaj-Saif, Abderaouf ; Rouiller, Eric

In: Experimental Brain Research, 2012, vol. 223, no. 3, p. 321-340

Influence of anti-Nogo-A antibody treatment on the reorganization of callosal connectivity of the premotor cortical areas following unilateral lesion of primary motor cortex (M1) in adult macaque monkeys

Hamadjida, Adjia ; Wyss, Alexander F. ; Mir, Anis ; Schwab, Martin E. ; Belhaj-Saif, Abderaouf ; Rouiller, Eric M.

In: Experimental Brain Research, 2012, vol. 223, no. 3, p. 321-340

Following unilateral lesion of the primary motor cortex, the reorganization of callosal projections from the intact hemisphere to the ipsilesional premotor cortex (PM) was investigated in 7 adult macaque monkeys, in absence of treatment (control; n = 4) or treated with function blocking antibodies against the neurite growth inhibitory protein Nogo-A (n = 3). After functional recovery, though...