In: European Journal of Applied Physiology, 2012, vol. 112, no. 1, p. 155-162
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In: Histochemistry and Cell Biology, 2008, vol. 130, no. 1, p. 141-155
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In: Cell and Tissue Research, 2003, vol. 314, no. 1, p. 107-117
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In: Cell and Tissue Research, 2006, vol. 323, no. 3, p. 395-404
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In: Arteriosclerosis, Thrombosis, and Vascular Biology, 2011, vol. 31, p. 2836-2844
Objective—The concept of vascular pruning, the “cuting-off” of vessels, is gaining importance due to expansion of angio-modulating therapies. The proangiogenic effects of vascular endothelial growth factor (VEGF) are broadly described, but the mechanisms of structural alterations by its downregulation are not known.Methods and Results—VEGF165-releasing hydrogels were applied onto the...
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In: American Journal of Pathology, 2009, vol. 173, p. 1173-1185
Inhibitors of angiogenesis and radiation induce compensatory changes in the tumor vasculature both during and after treatment cessation. To assess the responses to irradiation and vascular endothelial growth factor-receptor tyrosine kinase inhibition (by the vascular endothelial growth factor tyrosine kinase inhibitor PTK787/ZK222854), mammary carcinoma allografts were investigated by vascular...
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