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Optical and theoretical study of strand recognition by nucleic acid probes

Domljanovic, Ivana ; Taskova, Maria ; Miranda, Pâmella ; Weber, Gerald ; Astakhova, Kira

In: Communications Chemistry, 2020, vol. 3, no. 1, p. 111

Detection of nucleic acids is crucial to the study of their basic properties and consequently to applying this knowledge to the determination of pathologies such as cancer. In this work, our goal is to determine new trends for creating diagnostic tools for cancer driver mutations. Herein, we study a library of natural and modified oligonucleotide duplexes by a combination of optical and...