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Glomerular macrophages in human auto- and allo-immune nephritis

Moll, Solange ; Angeletti, Andrea ; Scapozza, Leonardo ; Cavalli, Andrea ; Ghiggeri, Gian Marco ; Prunotto, Marco

In: Cells, 2021, vol. 10, no. 3, p. 19 p

Macrophages are involved in tissue homeostasis. They participate in inflammatory episodes and are involved in tissue repair. Macrophages are characterized by a phenotypic heterogeneity and a profound cell plasticity. In the kidney, and more particularly within glomeruli, macrophages are thought to play a maintenance role that is potentially critical for preserving a normal glomerular structure....