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Evaluation of extracellular vesicle function during malaria infection

Andrea Hernández-Castañeda, María ; Mbagwu, Smart Ikechukwu ; Babatunde, Kehinde Adebayo ; Walch, Michael ; Filgueira, Luis ; Mantel, Pierre-Yves

In: JoVE (Journal of Visualized Experiments), 2018, no. 132, p. e57067

Malaria is a life-threatening disease caused by Plasmodium parasites, with P. falciparum being the most prevalent on the African continent and responsible for most malaria-related deaths globally. Several factors including parasite sequestration in tissues, vascular dysfunction, and inflammatory responses influence the evolution of the disease in malaria-infected people. P. falciparum-infected...