Université de Fribourg

Spatial and temporal analysis of meso- and microplastic pollution in the Ligurian and Tyrrhenian Seas

Caldwell, Jessica ; Muff, Livius F. ; Pham, Christopher K. ; Petri-Fink, Alke ; Rothen-Rutishauser, Barbara ; Lehner, Roman

In: Marine Pollution Bulletin, 2020, vol. 159, p. 111515

Areas like the Mediterranean coastlines, which have high population density, represent locations of high pollution risk for surrounding environments. Thus, this study aims to compare data on the abundance, size, and composition of buoyant plastic particles collected during two weeks in 2019 in the Ligurian and Tyrrhenian Seas with data from 2018. The results from 2019 show average meso- and ...

Université de Fribourg

A novel 3D intestine barrier model to study the immune response upon exposure to microplastics

Lehner, Roman ; Wohlleben, Wendel ; Septiadi, Dedy ; Landsiedel, Robert ; Petri‑Fink, Alke ; Rothen‑Rutishauser, Barbara

In: Archives of Toxicology, 2020, p. -

The plausibility of human exposure to microplastics has increased within the last years. Microplastics have been found in different food types including seafood, salt, sugar and beverages. So far, human health effects of microplastics after ingestion are unknown. Herein, we designed a novel, three- dimensional in vitro intestinal model consisting of the human intestinal epithelial cell lines...

Université de Fribourg

Assessing meso- and microplastic pollution in the Ligurian and Tyrrhenian Seas

Caldwell, Jessica ; Petri-Fink, Alke ; Rothen-Rutishauser, Barbara ; Lehner, Roman

In: Marine Pollution Bulletin, 2019, vol. 149, p. 110572

As the production of plastic products continues to increase, determining the fate of plastic waste in the environment is of high importance. Densely populated areas, such as Mediterranean coastlines, represent locations of high pollution risk for surrounding environments. Thus, this study aims to assess the abundance, size, and composition of floating meso- and microplastics collected during...

Université de Fribourg

Emergence of nanoplastic in the environment and possible impact on human health

Lehner, Roman ; Weder, Christoph ; Petri-Fink, Alke ; Rothen-Rutishauser, Barbara

In: Environmental Science & Technology, 2019, vol. 53, no. 4, p. 1748–1765

On account of environmental concerns, the fate and adverse effects of plastics have attracted considerable interest in the past few years. Recent studies have indicated the potential for fragmentation of plastic materials into nanoparticles, i.e., “nanoplastics,” and their possible accumulation in the environment. Nanoparticles can show markedly different chemical and physical properties...

Université de Fribourg

Biodistribution, clearance, and long‐term fate of clinically relevant nanomaterials

Bourquin, Joël ; Milosevic, Ana ; Hauser, Daniel ; Lehner, Roman ; Blank, Fabian ; Petri-Fink, Alke ; Rothen-Rutishauser, Barbara

In: Advanced Materials, 2018, p. -

Realization of the immense potential of nanomaterials for biomedical applications will require a thorough understanding of how they interact with cells, tissues, and organs. There is evidence that, depending on their physicochemical properties and subsequent interactions, nanomaterials are indeed taken up by cells. However, the subsequent release and/or intracellular degradation of the...

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1 Lehner, Rea