Mémoire de master : Université de Fribourg, 2018.
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In: Journal of Biological Rhythms, 2006, vol. 21(3), p. 169-176
In mammals, circadian rhythms in behavior and physiology are controlled by a central pacemaker, the SCN, and subordinated clocks throughout the body. On the molecular level, these clocks are based on transcriptional/translational feedback loops involving a set of clock genes that regulate their own transcription. Among the components driving the mammalian circadian clock are the Period 1...
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In: CHIMIA International Journal for Chemistry, 2019, vol. 73, no. 1, p. 12–16
Nanorattles and hollow nanocontainers have unique properties related to the presence of a void space inside the shell, which has been shown to improve the properties of materials for e.g. catalysis, drug release, sensor materials or lithium ion batteries. This article summarizes our recent progress in the synthesis of hollow silica, titania and ceria nanorattles and nanocontainers, eventually...
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In: Chemistry – A European Journal, 2020, vol. 26, no. 48, p. 10948–10971
Silver is an antimicrobial agent well known since antiquity. With the emergence of multiresistant bacteria, it has come back into the focus of research, and ionic as well as nano‐sized silver have been studied in vitro and in vivo. The results are controversial, silver being discussed as the “silver bullet” or a “wolf in sheep's clothing”. A thorough search of literature from...
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In: CHIMIA International Journal for Chemistry, 2018, vol. 72, no. 4, p. 249–252
Biomaterial-related infections remain a significant challenge in medicine. Antimicrobial materials on the basis of Ag nanoparticles represent a promising solution for this issue. Therefore several Ag-containing nanocontainers and nanorattles have been synthesized and characterized that exhibit remarkable control over the release of Ag+ as antimicrobial active species. Their biological...
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Mémoire de master : Université de Fribourg, 2019.
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In: Frontiers in Neurology, 2019, vol. 10, p. 617
Depression in Parkinson's Disease (PD) is a prevalent and invalidating symptom. Deep brain stimulation (DBS) allows for an improvement of PD motor features, but its effects on mood are difficult to predict. Here, we review the evidence regarding mood effects after DBS of either subthalamic nucleus (STN) or globus pallidus pars interna (GPi). Different influences of multiple factors contribute...
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In: Brain, 2017, vol. 140, no. 9, p. e57–e57
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In: Brain, 2017, vol. 140, no. 9, p. e57-e57
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In: Brain, 2016, vol. 139, no. 9, p. 2503–2515
Deep brain stimulation of the subthalamic nucleus is an established treatment for the motor symptoms of Parkinson’s disease. Given the frequent occurrence of stimulation- induced affective and cognitive adverse effects, a better understanding about the role of the subthalamic nucleus in non-motor functions is needed. The main goal of this study is to characterize anatomical circuits...
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