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Université de Fribourg

How clonal are clones? A quest for loss of heterozygosity during asexual reproduction in Daphnia magna

Dukić, Marinela ; Berner, Daniel ; Haag, Christoph R. ; Ebert, Dieter

In: Journal of Evolutionary Biology, 2019, vol. 32, no. 6, p. 619–628

Due to the lack of recombination, asexual organisms are predicted to accumulate mutations and show high levels of within‐individual allelic divergence (heterozygosity); however, empirical evidence for this prediction is largely missing. Instead, evidence of genome homogenization during asexual reproduction is accumulating. Ameiotic crossover recombination is a mechanism that could lead to...

Université de Fribourg

A high-density genetic map reveals variation in recombination rate across the genome of Daphnia magna

Dukić, Marinela ; Berner, Daniel ; Roesti, Marius ; Haag, Christoph R. ; Ebert, Dieter

In: BMC Genetics, 2016, vol. 17, p. 137

Recombination rate is an essential parameter for many genetic analyses. Recombination rates are highly variable across species, populations, individuals and different genomic regions. Due to the profound influence that recombination can have on intraspecific diversity and interspecific divergence, characterization of recombination rate variation emerges as a key resource for population...

Université de Fribourg

Local adaptation of sex induction in a facultative sexual crustacean: insights from QTL mapping and natural populations of Daphnia magna

Roulin, Anne C. ; Routtu, Jarkko ; Hall, Matthew D. ; Janicke, Tim ; Colson, Isabelle ; Haag, Christoph R. ; Ebert, Dieter

In: Molecular Ecology, 2013, vol. 22, no. 13, p. 3567–3579

Dormancy is a common adaptation in invertebrates to survive harsh conditions. Triggered by environmental cues, populations produce resting eggs that allow them to survive temporally unsuitable conditions. Daphnia magna is a crustacean that reproduces by cyclical parthenogenesis, alternating between the production of asexual offspring and the sexual reproduction of diapausing eggs (ephippia)....

Université de Fribourg

The impact of infection on host competition and its relationship to parasite persistence in a Daphnia microparasite system

Refardt, Dominik ; Ebert, Dieter

In: Evolutionary Ecology, 2012, vol. 26, no. 1, p. 95-107

Evolutionary studies often estimate fitness components with the aim to make predictions about the outcome of selection. Depending on the system and the question, different fitness components are used, but their usefulness for predicting the outcome of selection is rarely tested. Here we estimate host fitness components in different ways with the aim to test how well they agree with each other...

Université de Fribourg

Population genetics of duplicated alternatively spliced exons of the Dscam gene in Daphnia and Drosophila

Brites, Daniela ; Encinas-Viso, Francisco ; Ebert, Dieter ; Pasquier, Louis Du ; Haag, Christoph R.

In: PLoS ONE, 2011, vol. 6, no. 12, p. e27947

In insects and crustaceans, the Down syndrome cell adhesion molecule (Dscam) occurs in many different isoforms. These are produced by mutually exclusive alternative splicing of dozens of tandem duplicated exons coding for parts or whole immunoglobulin (Ig) domains of the Dscam protein. This diversity plays a role in the development of the nervous system and also in the immune system. Structural...

Université de Fribourg

Converging seasonal prevalence dynamics in experimental epidemics

Lass, Sandra ; Hottinger, Jürgen W. ; Fabbro, Thomas ; Ebert, Dieter

In: BMC Ecology, 2011, vol. 11, p. 14

Background Regular seasonal changes in prevalence of infectious diseases are often observed in nature, but the mechanisms are rarely understood. Empirical tests aiming at a better understanding of seasonal prevalence patterns are not feasible for most diseases and thus are widely lacking. Here, we set out to study experimentally the seasonal prevalence in an aquatic host-parasite system. The...