In: Cardiovascular Diabetology, 2014, vol. 13, no. 1, p. 113
Background Endothelial nitric oxide synthase (eNOS)-uncoupling links obesity-associated insulin resistance and type-II diabetes to the increased incidence of cardiovascular disease. Studies have indicated that increased arginase is involved in eNOS-uncoupling through competing with the substrate L-arginine. Given that arginase-II (Arg-II) exerts some of its biological functions through crosstalk...
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In: Obésité, 2014, p. 1–7
Objectives: To study, in obese subjects, the effect of diffuse ultrasound application in the abdominal area combined to muscular work on a vibrating platform. This dual method aims at accelerating the mobilisation of adipose tissue.Methods: 40 sedentary obese women, 18 to 55 years old, with a BMI ≥30 kg/m2 and ≤40 kg/m2 were randomized into 3 groups. 1) A control group (CONTR, n=13), 2) a...
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In: British Journal of Nutrition, 2011, vol. 105, no. 12, p. 1750-1763
The present study investigates whether excessive fat accumulation and hyperinsulinaemia during catch-up growth on high-fat diets are altered by n-6 and n-3 PUFA derived from oils rich in either linoleic acid (LA), α-linolenic acid (ALA), arachidonic acid (AA) or DHA. It has been shown that, compared with food-restricted rats refed a high-fat (lard) diet low in PUFA, those...
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In: Best Practice & Research Clinical Endocrinology & Metabolism, 2008, vol. 22, no. 1, p. 155-171
Catch-up growth early in life (after fetal, neonatal or infantile growth retardation) is a major risk factor for later obesity, type-2 diabetes and cardiovascular diseases. These risks are generally interpreted alongside teleological arguments that environmental exposures which hinder growth early in life lead to programming of ‘thrifty mechanisms’ that are adaptive during the period of...
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