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Consortium of Swiss Academic Libraries

The zeros of random polynomials cluster uniformly near the unit circle

Hughes, C P.

In: Compositio Mathematica, 2008, vol. 144, no. 3, p. 734-746

Consortium of Swiss Academic Libraries

Zellen des Immunsystems: vom Polarkreis ins All

Layer, Liliana ; Ullrich, Oliver

In: BIOspektrum, 2011, vol. 17, no. 4, p. 437-439

Université de Fribourg

The zebrafish heart regenerates after cryoinjury-induced myocardial infarction

Chablais, Fabian ; Veit, Julia ; Rainer, Gregor ; Jaźwińska, Anna

In: BMC Developmental Biology, 2011, vol. 11, p. 21

Background: In humans, myocardial infarction is characterized by irreversible loss of heart tissue, which becomes replaced with a fibrous scar. By contrast, teleost fish and urodele amphibians are capable of heart regeneration after a partial amputation. However, due to the lack of a suitable infarct model, it is not known how these animals respond to myocardial infarction.Results: Here, we have...

Université de Fribourg

Zebrafish fin regeneration involves transient serotonin synthesis

König, Désirée ; Jaźwińska, Anna

In: Wound Repair and Regeneration, 2019, p. wrr.12719

The zebrafish is a vertebrate organism capable of regenerating many of its organs. Notably, it can undergo epimorphic regeneration of its fins after amputation. This process occurs through the formation of a wound epithelium and the dedifferentiation of mesenchymal and bone‐forming cells, which form a proliferative blastema. Here, we report that the entry into the regenerative process...

Université de Fribourg

Zebrafish fin regeneration after cryoinjury-induced tissue damage

Chassot, Bérénice ; Pury, David ; Jaźwińska, Anna

In: Biology Open, 2016, vol. 5, no. 6, p. 819–828

Although fin regeneration following an amputation procedure has been well characterized, little is known about the impact of prolonged tissue damage on the execution of the regenerative programme in the zebrafish appendages. To induce histolytic processes in the caudal fin, we developed a new cryolesion model that combines the detrimental effects of freezing/thawing and ischemia. In contrast...

Université de Fribourg

Zebrafish caudal fin angiogenesis assay—advanced quantitative assessment including 3-way correlative microscopy

Hlushchuk, Ruslan ; Brönnimann, Daniel ; Shokiche, Carlos Correa ; Schaad, Laura ; Triet, Ramona ; Jazwinska, Anna ; Tschanz, Stefan A. ; Djonov, Valentin

In: PLOS ONE, 2016, vol. 11, no. 3, p. e0149281

Background: Researchers evaluating angiomodulating compounds as a part of scientific projects or pre-clinical studies are often confronted with limitations of applied animal models. The rough and insufficient early-stage compound assessment without reliable quantification of the vascular response counts, at least partially, to the low transition rate to clinics. Objective: To establish an...