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Université de Fribourg

Cytotoxic flavonoids and other constituents from the stem bark of Ochna schweinfurthiana

Ndongo, Joseph T. ; Issa, Mark E. ; Messi, Angelique N. ; Mbing, Joséphine Ngo ; Cuendet, Muriel ; Pegnyemb, Dieudonné Emmanuel ; Bochet, Christian G.

In: Natural Product Research, 2015, vol. 29, no. 17, p. 1684-1687

Seven flavonoids, hemerocallone (1), 6,7-dimethoxy-3′,4′-dimethoxyisoflavone (2), amentoflavone (4), agathisflavone (6), cupressuflavone (8), robustaflavone (9) and epicatechin (10), together with three other compounds, lithospermoside (3), β-D- fructofuranosyl-α-D-glucopyranoside (5) and 3β-O-D-glucopyranosyl-β-stigmasterol (7), were isolated from the ethyl acetate extract of the stem...

Università della Svizzera italiana

High-level services for networks-on-chip

Fiorin, Leandro ; Sami, Mariagiovanna (Dir.) ; Silvano, Cristina (Codir.)

Thèse de doctorat : Università della Svizzera italiana, 2012 ; 2012INFO010.

Future technology trends envision that next-generation Multiprocessors Systems-on- Chip (MPSoCs) will be composed of a combination of a large number of processing and storage elements interconnected by complex communication architectures. Communication and interconnection between these basic blocks play a role of crucial importance when the number of these elements increases. Enabling reliable...

Università della Svizzera italiana

Justifying age thresholds for mammographic screening: an application of pragma-dialectical argumentation theory

Schulz, Peter J. ; Meuffels, Bert

In: Health Communication, 2012, vol. 2, no. 2012, p. 167-178

Information campaigns on breast cancer screening in the Netherlands need to convince women above 50 years of age to have biannual mammography, and women below 50 years of age that regular mammograms are not recommended for them. This article reports the results of two experiments in which the construction of the persuasive messages was informed by argumentation-theoretical insights. No...

Università della Svizzera italiana

The parallel event loop model and runtime : a parallel programming model and runtime system for safe event-based parallel programming

Bonetta, Daniele ; Pautasso, Cesare (Dir.)

Thèse de doctorat : Università della Svizzera italiana, 2014 ; 2014INFO017.

Recent trends in programming models for server-side development have shown an increasing popularity of event-based single- threaded programming models based on the combination of dynamic languages such as JavaScript and event-based runtime systems for asynchronous I/O management such as Node.JS. Reasons for the success of such models are the simplicity of the single-threaded event-based...

Università della Svizzera italiana

Voronoi diagrams in the max-norm : algorithms, implementation, and applications

Dey, Sandeep Kumar ; Papadopoulou, Evanthia (Dir.)

Thèse de doctorat : Università della Svizzera italiana, 2015 ; 2015INFO007.

Voronoi diagrams and their numerous variants are well-established objects in computational geometry. They have proven to be extremely useful to tackle geometric problems in various domains such as VLSI CAD, Computer Graphics, Pattern Recognition, Information Retrieval, etc. In this dissertation, we study generalized Voronoi diagram of line segments as motivated by applications in VLSI Computer...

Università della Svizzera italiana

Local time stepping on high performance computing architectures : mitigating CFL bottlenecks for large-scale wave propagation

Rietmann, Max ; Schenk, Olaf (Dir.)

Thèse de doctorat : Università della Svizzera italiana, 2015 ; 2015INFO006.

Modeling problems that require the simulation of hyperbolic PDEs (wave equations) on large heterogeneous domains have potentially many bottlenecks. We attack this problem through two techniques: the massively parallel capabilities of graphics processors (GPUs) and local time stepping (LTS) to mitigate any CFL bottlenecks on a multiscale mesh. Many modern supercomputing centers are installing...

Université de Fribourg

Pathways from dieting to weight regain, to obesity and to the metabolic syndrome: an overview

Dulloo, Abdul G. ; Montani, Jean-Pierre

In: Obesity Reviews, 2015, vol. 16, p. 1–6

Every year, scores of millions of people – as diverse as obese and lean, teenagers and older adults, sedentary and elite athletes, commoners and celebrities – attempt to lose weight on some form of diet. They are often encouraged by their parents, friends, health professionals, training coaches, a media that promotes a slim image and a diet- industry that in Europe and United States alone...

Université de Fribourg

Comparison of a novel biodegradable polymer sirolimus-eluting stent With a durable polymer everolimus-eluting stent results of the randomized BIOFLOW-II trial

Windecker, Stephan ; Haude, Michael ; Neumann, Franz-Josef ; Stangl, karl ; Witzenbichler, Bernhard ; Slagboom, Ton ; Sabaté, Manel ; Goicolea, Javier ; Barragan, Paul ; Cook, Stéphane ; Piot, Christophe ; Richardt, Gert ; Merkely, Béla ; Schneider, Henrik ; Bilger, Johannes ; Erne, Paul ; Waksman, Ron ; Zaugg, Serge ; Jüni, Peter ; Lefèvre, Thierry

In: Circulation: Cardiovascular Interventions, 2015, vol. 8, no. 2, p. e001441

Background—Biodegradable polymers for release of antiproliferative drugs from drug-eluting stents aim to improve vascular healing. We assessed noninferiority of a novel ultrathin strut drug-eluting stent releasing sirolimus from a biodegradable polymer (Orsiro, O-SES) compared with the durable polymer Xience Prime everolimus-eluting stent (X-EES) in terms of the primary end...

Université de Fribourg

Perception of co-speech gestures in aphasic patients: A visual exploration study during the observation of dyadic conversations

Preisig, Basil C. ; Eggenberger, Noëmi ; Zito, Giuseppe ; Vanbellingen, Tim ; Schumacher, Rahel ; Hopfner, Simone ; Nyffeler, Thomas ; Gutbrod, Klemens ; Annoni, Jean-Marie ; Bohlhalter, Stephan ; Müri, René M.

In: Cortex, 2015, vol. 64, p. 157–168

Co-speech gestures are part of nonverbal communication during conversations. They either support the verbal message or provide the interlocutor with additional information. Furthermore, they prompt as nonverbal cues the cooperative process of turn taking. In the present study, we investigated the influence of co-speech gestures on the perception of dyadic dialogue in aphasic patients. In...

Università della Svizzera italiana

Resource management of replicated service systems provisioned in the cloud

Björkqvist, Mathias ; Binder, Walter (Dir.)

Thèse de doctorat : Università della Svizzera italiana, 2015 ; 2015INFO005.

Service providers seek scalable and cost-effective cloud solutions for hosting their applications. Despite significant recent advances facilitating the deployment and management of services on cloud platforms, a number of challenges still remain. Service providers are confronted with time-varying requests for the provided applications, inter- dependencies between different components,...