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    Université de Fribourg

    Functional analysis of the yeast "Saccharomyces cerevisiae" Gpi8 protein and characterization of the purified GPI-transamidase complex

    Fraering, Patrick ; Conzelmann, Andreas (Dir.) ; van der Goot, Françoise Gisou (Codir.) ; Puoti, Alessandro (Codir.)

    Thèse de doctorat : Université de Fribourg, 2001 ; no 1354.

    Many glycoproteins of lower and higher eucaryotes are attached to the plasma membrane by means of a glycosylphosphatidylinositol (GPI). GPI anchoring of proteins is essential for the growth of Saccharomyces cerevisiae . S.cerevisiae contains about 70 open reading frames predicting GPI proteins and many of these have been found to be cell wall glycoproteins. The precursors of GPI anchored proteins...