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Université de Fribourg

Powerful fast triggerable 6 μm laser for the muonic hydrogen 2S-Lamb shift experiment

Antognini, A. ; Amaro, F. D. ; Biraben, F. ; Cardoso, J. M. R. ; Conde, C. A. N. ; Covita, D. S. ; Dax, A. ; Dhawan, S. ; Fernandes, L. M. P. ; Hänsch, T. W. ; Hughes, V. W. ; Huot, Olivier ; Indelicato, P. ; Julien, L. ; Knowles, Paul E. ; Kottmann, F. ; Liu, Y.-W. ; Lopes, J. A. M. ; Ludhova, Livia ; Monteiro, C. M. B. ; Mulhauser, Françoise ; Nez, F. ; Perry, B. N. ; Pohl, R. ; Rabinowitz, P. ; Santos, J. M. F. dos ; Schaller, Lukas A. ; Schwob, C. ; Taqqu, D. ; Veloso, J. F. C. A.

In: Optics Communications, 2005, vol. 253 (4-6), p. 362-374

Laser spectroscopy of the 2S-Lamb shift in muonic hydrogen (μ−p) is being performed at the Paul Scherrer Institute, Switzerland, to determine the root-mean-square (rms) proton charge radius with 10−3 precision. A multistage laser system has been developed which provides 0.2 mJ pulse energy tunable at 6 μm wavelength. An excimer pumped dye laser is used to drive a...

Université de Fribourg

Gpi17p does not stably interact with other subunits of glycosylphosphatidylinositol transamidase in Saccharomyces cerevisiae

Zhu, Yonghua ; Fraering, Patrick ; Vionnet, Christine ; Conzelmann, Andreas

In: Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2005, vol. 1735(1), p. 79

Homologues of Gpi8p, Gaa1p, Gpi16p, Gpi17p, and Cdc91p are essential components of the GPI transamidase complex that adds glycosylphosphatidylinositols (GPIs 1) to newly synthesized proteins in the ER. In mammalian cells, these five subunits remain stably associated with each other in detergent. In yeast, we find no stable stoichiometric association of Gpi17p with the Gpi8p–Gpi16p–Gaa1p core...

Université de Fribourg

Enhanced passive Ca²⁺ reabsorption and reduced Mg²⁺ channel abundance explains thiazide-induced hypocalciuria and hypomagnesemia

Nijenhuis, Tom ; Vallon, Volker ; Kemp van der, Annemiete W.C.M. ; Loffing, Johannes ; Hoenderop, Joost G.J. ; Bindels, René J.M.

In: The Journal of Clinical Investigation, 2005, vol. 115(6), p. 1651

Thiazide diuretics enhance renal Na⁺ excretion by blocking the Na⁺-Cl⁻ cotransporter (NCC), and mutations in NCC result in Gitelman syndrome. The mechanisms underlying the accompanying hypocalciuria and hypomagnesemia remain debated. Here, we show that enhanced passive Ca²⁺ transport in the proximal tubule rather than active Ca²⁺ transport in distal convolution explains...

Université de Fribourg

400 years of debris flow activity and triggering weather conditions: Ritigraben VS, Switzerland

Stoffel, Markus ; Lièvre, Igor ; Conus, Delphine ; Grichting, Michael A. ; Raetzo, Hugo ; Gärtner, Holger W. ; Monbaron, Michel

In: Arctic Antarctic and Alpine Research, 2005, vol. 37(3), p. 387-395

Three major rainfall events have caused considerable damage in the Valais region (Swiss Alps) since 1987. While important debris flows originating from periglacial environments were recorded during the August 1987 and September 1993 rainfall events, no debris flows occurred in October 2000. This paper aims at putting these large area events and the apparent increase in debris flow frequency into...

Université de Fribourg

Site selection for OWL using past, present, and future climate information

Graham, Edward ; Sarazin, Marc S. ; Beniston, Martin ; Collet, Claude ; Hayoz, Michael ; Neun, Moritz ; Goyette, Stéphane

In: Proceedings of SPIE, 2004, vol. 5489, p. 102

Selection of an ideal site for the new generation of Overwhelmingly Large (OWL) telescopes is dependent on many climatological and meteorological parameters. Among these are cloud cover, atmospheric humidity, aerosol content, air temperature, airflow direction, strength and turbulence. Even relatively minor changes in weather patterns can have a significant effect on seeing conditions. A...

Université de Fribourg

Climate-based site selection for a very large telescope using GIS techniques

Graham, Edward ; Sarazin, Marc S. ; Beniston, Martin ; Collet, Claude ; Hayoz, Michael ; Neun, Moritz ; Casals, Paula

In: Meteorological Applications, 2005, vol. 12, p. 77

Astronomical research at present requires that a telescope with an aperture diameter of between 50 and 100 metres be constructed within the next 10 years or so. This new generation of telescopes will be called OWL (Overwhelmingly Large), and it represents one order of magnitude increase in size over today's telescopes. Selection of an ideal site for this giant telescope is dependent on many...

Université de Fribourg

Novel HEXOL-type cyclometallated iridium(III) complexes: stereoselective synthesis and structure elucidation

Yang, Liangru ; Zelewsky, Alexander von ; Stoeckli-Evans, Helen

In: Chemical Communications, 2005, vol. (33), p. 4155

Two diastereoisomers of tetranuclear cyclometallated iridium complexes, either having an inner core of HEXOL-type [Ir(IrCl₂)₃]⁶⁺ unit and a surface of six chiral, didentate, cyclometallated ligands, are stereoselectively synthesized from an enantiopure pinenopyridine derivative.

Université de Fribourg

Analyzing rockfall activity (1600–2002) in a protection forest—a case study using dendrogeomorphology

Stoffel, Markus ; Schneuwly, Dominique M. ; Bollschweiler, Michelle ; Lièvre, Igor ; Delaloye, Reynald ; Myint, Moe ; Monbaron, Michel

In: Geomorphology, 2005, vol. 68(3-4), p. 224

For the first time, dendrogeomorphology has been used to investigate spatial and temporal variations of rockfall activity in a protection forest. We report results of 564 cores from 135 severely injured Larix decidua Mill. trees on the west-facing Täschgufer slope, Swiss Alps. While trees sampled reached an age of 297 years on average, the oldest one attained breast height in AD 1318. For...

Université de Fribourg

Mont Blanc and Aiguilles Rouges geology of their polymetamorphic basement (external massifs, Westerns Alps, France-Switzerland)

Raumer, Jürgen F. von ; Bussy, François

In: Mémoires de Géologie (Lausanne), 2004, vol. 42, p. 1-210

The Aiguilles Rouges and Mont Blanc external massifs belong to the pre-Mesozoic basement areas of the external domain of the Alps. Before their involvement into the Alpine building (basement nappes) they registered a multiple geological evolution comprising the deposition of Neoproterozoic to Cambrian sediments and emplacement of granitoid and metabasic to ultramafic magmatic rocks of Early...

Université de Fribourg

The Aptian, Albian and Cenomanian of Roter Sattel, Romandes Prealps, Switzerland: a high-resolution record of oceanographic changes

Strasser, André ; Caron, Michèle ; Gjermeni, Maksim

In: Cretaceous Research, 2001, vol. 22 (2), p. 173

The Aptian–Lower Turonian hemipelagic sediments of Roter Sattel in the Swiss Prealps are well dated by planktonic foraminifera. Stacking pattern of the limestone-marl alternations and facies evolution allow the identification of sequence boundaries, transgressive surfaces, and maximum-flooding events or condensed sections on at least two hierarchical levels. Calibrated by a precise...