In: Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms, 2015, vol. 1849, no. 11, p. 1329–1339
Gene expression regulation by intracellular stimulus-activated protein kinases is essential for cell adaptation to environmental changes. There are three PKA catalytic subunits in Saccharomyces cerevisiae: Tpk1, Tpk2, and Tpk3 and one regulatory subunit: Bcy1. Previously, it has been demonstrated that Tpk1 and Tpk2 are associated with coding regions and promoters of target genes in a carbon...
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In: Journal Of Experimental Botany, 2014, vol. 65, no. 10, p. 2769-2784
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In: Cell and Tissue Research, 2014, vol. 356, no. 3, p. 495-505
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In: Cellular and Molecular Life Sciences, 2012, vol. 69, no. 13, p. 2173-2187
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In: FEBS Letters, 2011, p. -
In mammals, higher order chromatin structures are critical for downsizing the genome (packaging) so that the nucleus can be small. The adjustable density of chromatin also regulates gene expression, thus this post-genetic molecular mechanism is one of the routes by which phenotype is shaped. Phenotypes that arise without a concomitant mutation of the underlying genome are termed epigenetic...
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