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Probing the role of point mutations in the cyp51A gene from Aspergillus fumigatus in the model yeast Saccharomyces cerevisiae

Alcazar-Fuoli, L. ; Mellado, E. ; Cuenca-Estrella, M. ; Sanglard, D.

In: Medical Mycology, 2011, vol. 49, no. 3, p. 276-284

Polyglutamine tracts as modulators of transcriptional activation from yeast to mammals

Atanesyan, Lilit ; Günther, Viola ; Dichtl, Bernhard ; Georgiev, Oleg ; Schaffner, Walter

In: Biological Chemistry, 2012, vol. 393, no. 1-2, p. 63-70

PKA-chromatin association at stress responsive target genes from Saccharomyces cerevisiae

Baccarini, Leticia ; Martínez-Montañés, Fernando ; Rossi, Silvia ; Proft, Markus ; Portela, Paula

In: Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms, 2015, vol. 1849, no. 11, p. 1329–1339

Gene expression regulation by intracellular stimulus-activated protein kinases is essential for cell adaptation to environmental changes. There are three PKA catalytic subunits in Saccharomyces cerevisiae: Tpk1, Tpk2, and Tpk3 and one regulatory subunit: Bcy1. Previously, it has been demonstrated that Tpk1 and Tpk2 are associated with coding regions and promoters of target genes in a carbon...

Multiple functions of inositolphosphorylceramides in the formation and intracellular transport of glycosylphosphatidylinositol-anchored proteins in yeast

Bosson, Régine ; Conzelmann, Andreas

In: Biochemical Society Symposia, 2007, vol. 74, p. 199-209

The mature sphingolipids of yeast consist of IPCs (inositolphosphorylceramides) and glycosylated derivatives thereof. Beyond being an abundant membrane constituent in the organelles of the secretory pathway, IPCs are also used to constitute the lipid moiety of the majority of GPI (glycosylphosphatidylinositol) proteins, while a minority of GPI proteins contain PI (phosphatidylinositol). Thus...

Ordered assembly of the asymmetrically branched lipid-linked oligosaccharide in the endoplasmic reticulum is ensured by the substrate specificity of the individual glycosyltransferases

Burda, Patricie ; Jakob, Claude A. ; Beinhauer, Jens ; Hegemann, Johannes H. ; Aebi, Markus

In: Glycobiology, 1999, vol. 9, no. 6, p. 617-625

GPI anchor biosynthesis in yeast: phosphoethanolamine is attached to the α1,4-linked mannose of the complete precursor glycophospholipid

Canivenc-Gansel, Elisabeth ; Imhof, Isabella ; Reggiori, Fulvio ; Burda, Patricie ; Conzelmann, Andreas ; Benachour, Abdellah

In: Glycobiology, 1998, vol. 8, no. 8, p. 761-770

Control of yeast fed-batch process through regulation of extracellular ethanol concentration

Cannizzaro, Christopher ; Valentinotti, Sergio ; von Stockar, Urs

In: Bioprocess and Biosystems Engineering, 2004, vol. 26, no. 6, p. 377-383

The caveolin-binding motif of the pathogen-related yeast protein Pry1, a member of the CAP protein superfamily, is required for in vivo export of cholesteryl acetate

Choudhary, Vineet ; Darwiche, Rabih ; Gfeller, David ; Zoete, Vincent ; Michielin, Olivier ; Schneiter, Roger

In: Journal of Lipid Research, 2014, vol. 55, no. 5, p. 883-894

Proteins belonging to the CAP superfamily are present in all kingdoms of life and have been implicated in different physiological processes. Their molecular mode of action, however, is poorly understood. Saccharomyces cerevisiae expresses three members of this superfamily, pathogen-related yeast (Pry)1, -2, and -3. We have recently shown that Pry function is required for the secretion of...

Monitoring sterol uptake, acetylation, and export in yeast

Choudhary, Vineet ; Schneiter, Roger

In: Methods in Molecular Biology, 2009, vol. 580, p. 221-232

Sterols are essential lipid components of eukaryotic membranes. They are synthesized in the endoplasmatic reticulum (ER) from where they are efficiently transported to the plasma membrane, which harbors ~90% of the free sterol pool of the cell. The molecular mechanisms that govern this lipid transport, however, are not well characterized and are challenging to analyze. Saccharomyces cerevisiae...

Budding yeast as a model organism to study the effects of age

Denoth Lippuner, Annina ; Julou, Thomas ; Barral, Yves

In: FEMS Microbiology Reviews, 2014, vol. 38, no. 2, p. 300-325