Université de Fribourg

Uptake and intracellular fate of peptide surface-functionalized silica hybrid magnetic nanoparticles in vitro

Digigow, Reinaldo G. ; Vanhecke, Dimitri ; Rothen-Rutishauser, Barbara ; Clift, Martin J.D. ; Petri-Fink, Alke

In: Particle & Particle Systems Characterization, 2015, vol. 32, no. 2, p. 188–196

Recently, the use of nanomaterials as intracellular targeting tools for theranostics has gained heightened interest. Despite the clear advantages posed by surface-functionalized nanoparticles (NPs) in this regard, limited understanding currently exists due to difficulties in reliably synthesizing NPs with surface functionalizations adequate for use in such applications, as well as the manner of...