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    Université de Fribourg

    Complete genome sequence of the clinical strain Acinetobacter baumannii R2090 Carrying the chromosomally encoded Metallo-β-Lactamase Gene blaNDM-1

    Krahn, Thomas ; Wibberg, Daniel ; Maus, Irena ; Winkler, Anika ; Nordmann, Patrice ; Pühler, Alfred ; Poirel, Laurent ; Schlüter, Andreas

    In: Genome Announcements, 2016, vol. 3, no. 5, p. e01008-15

    Acinetobacter baumannii is an emerging human pathogen causing nosocomial and community-acquired infections. Here, we present the complete genome sequence of the clinical A. baumannii strain R2090 carrying the metallo-β-lactamase gene blaNDM-1 in its chromosome within the transposon Tn125.

    Université de Fribourg

    Complete genome sequencing of Acinetobacter baumannii str. K50 disclosed the large conjugative plasmid pK50a encoding the carbapenemase OXA-23 and the extended-spectrum β–lactamase GES-11

    Wibberg, Daniel ; Salto, Ileana P. ; Eikmeyer, Felix G. ; Maus, Irena ; Winkler, Anika ; Nordmann, Patrice ; Pühler, Alfred ; Poirel, Laurent ; Schlüter, Andreas

    In: Antimicrobial Agents and Chemotherapy, 2018, p. AAC.00212-18

    Multidrug-resistant (MDR) Acinetobacter baumannii strains appeared as serious emerging nosocomial pathogens in clinical environments and especially in intensive care units (ICUs). A. baumannii strain K50 recovered from a hospitalized patient in Kuwait exhibited resistance to carbapenems, and additionally to ciprofloxacin, chloramphenicol, sulfonamides, amikacin and gentamicin. Genome...

    Université de Fribourg

    Intraspecies transfer of the chromosomal Acinetobacter baumannii blaNDM-1 carbapenemase gene

    Krahn, Thomas ; Wibberg, Daniel ; Maus, Irena ; Winkler, Anika ; Bontron, Séverine ; Sczyrba, Alexander ; Nordmann, Patrice ; Pühler, Alfred ; Poirel, Laurent ; Schlüter, Andreas

    In: Antimicrobial Agents and Chemotherapy, 2016, vol. 60, no. 5, p. 3032–3040

    The species Acinetobacter baumannii is one of the most important multidrug-resistant human pathogens. To determine its virulence and antibiotic resistance determinants, the genome of the nosocomial blaNDM-1-positive A. baumannii strain R2090 originating from Egypt was completely sequenced. Genome analysis revealed that strain R2090 is highly related to the...