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The neXtProt peptide uniqueness checker: a tool for the proteomics community

Schaeffer, Mathieu ; Gateau, Alain ; Teixeira, Daniel ; Michel, Pierre-André ; Zahn-Zabal, Monique ; Lane, Lydie ; Hancock, John ; Hancock, John

In: Bioinformatics, 2017, vol. 33, no. 21, p. 3471-3472

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    Titel
    • The neXtProt peptide uniqueness checker: a tool for the proteomics community
    Autor
    • Schaeffer, Mathieu. Department of Human Protein Science, Faculty of Medicine, University of Geneva, Geneva, Switzerland
    • Gateau, Alain. CALIPHO Group, SIB Swiss Institute of Bioinformatics, CMU, Geneva 4, Switzerland
    • Teixeira, Daniel. CALIPHO Group, SIB Swiss Institute of Bioinformatics, CMU, Geneva 4, Switzerland
    • Michel, Pierre-André. CALIPHO Group, SIB Swiss Institute of Bioinformatics, CMU, Geneva 4, Switzerland
    • Zahn-Zabal, Monique. CALIPHO Group, SIB Swiss Institute of Bioinformatics, CMU, Geneva 4, Switzerland
    • Lane, Lydie. Department of Human Protein Science, Faculty of Medicine, University of Geneva, Geneva, Switzerland
    • Hancock, John. Department of Human Protein Science, Faculty of Medicine, University of Geneva, Geneva, Switzerland
    • Hancock, John. Department of Human Protein Science, Faculty of Medicine, University of Geneva, Geneva, Switzerland
    Dokumententyp
    • Postprint
    OAI-PMH-ID
    • oai:doc.rero.ch:332804
    Summary
    Abstract Summary The neXtProt peptide uniqueness checker allows scientists to define which peptides can be used to validate the existence of human proteins, i.e. map uniquely versus multiply to human protein sequences taking into account isobaric substitutions, alternative splicing and single amino acid variants. Availability and implementation The pepx program is available at https://github.com/calipho-sib/pepx and can be launched from the command line or through a cgi web interface. Indexing requires a sequence file in FASTA format. The peptide uniqueness checker tool is freely available on the web at https://www.nextprot.org/tools/peptide-uniqueness-checker and from the neXtProt API at https://api.nextprot.org/.