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Tonotopic Gradients in Human Primary Auditory Cortex: Concurring Evidence From High-Resolution 7T and 3T fMRI

Da Costa, Sandra ; Saenz, Melissa ; Clarke, Stephanie ; van der Zwaag, Wietske

In: Brain Topography, 2015, vol. 28, no. 1, p. 66-69

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    Titre
    • Tonotopic Gradients in Human Primary Auditory Cortex: Concurring Evidence From High-Resolution 7T and 3T fMRI
    Auteur
    • Da Costa, Sandra. Service de Neuropsychologie et de Neuroréhabilitation, Département des Neurosciences Cliniques, CHUV, Hôpital Nestlé, Université de Lausanne, Avenue Pierre Decker 5, 1011, Lausanne, Switzerland
    • Saenz, Melissa. LREN, Département des Neurosciences Cliniques, CHUV, Université de Lausanne, Mont Paisible 16, 1011, Lausanne, Switzerland
    • Clarke, Stephanie. Service de Neuropsychologie et de Neuroréhabilitation, Département des Neurosciences Cliniques, CHUV, Hôpital Nestlé, Université de Lausanne, Avenue Pierre Decker 5, 1011, Lausanne, Switzerland
    • van der Zwaag, Wietske. Centre d'Imagerie BioMédicale (CIBM), EPFL et Universités de Lausanne et de Genève, Bâtiment CH, Station 6, 1015, Lausanne, Switzerland
    Type de document
    • Postprint
    Langue
    • Anglais
    Publié dans
    • Brain Topography, 2015, vol. 28, no. 1, p. 66-69. Springer US; http://www.springer-ny.com
    Autre version électronique
    Identifiant OAI-PMH
    • oai:doc.rero.ch:332105
    Summary
    The tonotopic representations within the primary auditory cortex (PAC) have been successfully mapped with ultra-high field fMRI. Here, we compared the reliability of this tonotopic mapping paradigm at 7T with 1.5mm spatial resolution with maps acquired at 3T with the same stimulation paradigm, but with spatial resolutions of 1.8 and 2.4mm. For all subjects, the mirror-symmetric gradients within PAC were highly similar at 7T and 3T and across renderings at different spatial resolutions; albeit with lower percent signal changes at 3T. In contrast, the frequency maps outside PAC tended to suffer from a reduced BOLD contrast-to-noise ratio at 3T for a 1.8mm voxel size, while robust at 2.4mm and at 1.5mm at 7T. Overall, our results showed the robustness of the phase-encoding paradigm used here to map tonotopic representations across scanners.