Disrupted prediction errors index social deficits in autism spectrum disorder
Balsters, Joshua H. ; Apps, Matthew A J. ; Bolis, Dimitris ; Lehner, Rea ; Gallagher, Louise ; Wenderoth, Nicole
In: Brain, 2017, vol. 140, no. 1, p. 235-246
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- In healthy individuals the anterior cingulate gyrus signals social prediction errors: discrepancies between an actual outcome and the perceived expectations of another person. Balsters et al. demonstrate that this crucial social signal is altered in individuals with autism, and that variability in social prediction error signalling indexes social symptom severity.