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Quantitative assessment of a second-generation cryoballoon ablation catheter with new cooling technology—a perspective on potential implications on outcome

Knecht, Sven ; Kühne, Michael ; Osswald, Stefan ; Sticherling, Christian

In: Journal of Interventional Cardiac Electrophysiology, 2014, vol. 40, no. 1, p. 17-21

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    Titre
    • Quantitative assessment of a second-generation cryoballoon ablation catheter with new cooling technology—a perspective on potential implications on outcome
    Auteur
    • Knecht, Sven. Cardiology/Electrophysiology, University Hospital Basel, Petersgraben 4, 4031, Basel, Switzerland
    • Kühne, Michael. Cardiology/Electrophysiology, University Hospital Basel, Petersgraben 4, 4031, Basel, Switzerland
    • Osswald, Stefan. Cardiology/Electrophysiology, University Hospital Basel, Petersgraben 4, 4031, Basel, Switzerland
    • Sticherling, Christian. Cardiology/Electrophysiology, University Hospital Basel, Petersgraben 4, 4031, Basel, Switzerland
    Type de document
    • Postprint
    Langue
    • Anglais
    Publié dans
    • Journal of Interventional Cardiac Electrophysiology, 2014, vol. 40, no. 1, p. 17-21. Springer US; http://www.springer-ny.com
    Autre version électronique
    Identifiant OAI-PMH
    • oai:doc.rero.ch:325118
    Summary
    Purpose: The purpose of this study was to assess the differences in cooling behavior between the first-generation cryoballoon (CB-1G) and the second-generation cryoballoon (CB-2G) quantitatively to understand the freezing capabilities and to benefit from the improved efficacy of the CB-2G in patients with atrial fibrillation. Methods: We analyzed quantitatively the ice formation of the CB-1G and CB-2G catheters in vitro in a 37°C warm water bath during freezing for 60, 120, 180, 240, and 300s, respectively. Results: The mean-covered surface area and the relative coverage of the ice spots on the CB-2G were significantly different from the spots on the CB-1G for the 28-mm CBs but not for the 23-mm CBs. Whereas for the CB-1G, the ice formation was discontiguous with four isolated ice spots; the CB-2G showed a contiguous ice cap covering the entire distal part including the pole of the balloon. No homogeneous cooling behavior could be observed at the equatorial level with both catheters. Temporal differences on the ice formation could be observed for the 28-mm CB-2G but not for the 23-mm CB-2G. Conclusion: The new-generation CB-2G showed more powerful and homogeneous cooling behavior, especially for the 28-mm CB. Whether this translates into higher long-term success rates is currently unknown. The impact of the more effective cooling and the longer dissolving duration of the ice cap of the new-generation CB-2G on procedural safety needs to be investigated.