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Drug Hypersensitivity Syndrome toCarbamazepine and Human Herpes Virus 6 Infection: Case Reportand Literature Review

Zeller, A. ; Schaub, N. ; Steffen, I. ; Battegay, E. ; Hirsch, H. ; Bircher, A.

In: Infection, 2003, vol. 31, no. 4, p. 254-256

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    Title
    • Drug Hypersensitivity Syndrome toCarbamazepine and Human Herpes Virus 6 Infection: Case Reportand Literature Review
    Author
    • Zeller, A.. Outpatient Dept. of Internal Medicine, University Hospital Basel, Switzerland
    • Schaub, N.. Allergy Unit, Dept. of Dermatology, University Hospital Basel, Petersgraben 4, CH-4031, Basel, Switzerland
    • Steffen, I.. Institute for Medical Microbiology, University of Basel, Switzerland
    • Battegay, E.. Outpatient Dept. of Internal Medicine, University Hospital Basel, Switzerland
    • Hirsch, H.. Dept. of Internal Medicine, Division of Infectious Diseases, University Hospital Basel, Switzerland
    • Bircher, A.. Allergy Unit, Dept. of Dermatology, University Hospital Basel, Petersgraben 4, CH-4031, Basel, Switzerland
    Document Type
    • Postprint
    Classification
    • Health
    OAI-PMH Identifier
    • oai:doc.rero.ch:322408
    Summary
    Abstract.: We describe a patient with a drug-induced hypersensitivity syndrome to carbamazepine and a concomitant active infection with human herpes virus 6 (HHV-6). The potential role of HHV-6 regarding the drug-induced hypersensitivity syndrome is discussed and the main clinical features of this potentially fatal adverse drug reaction are highlighted