Carcinoma ex pleomorphic adenoma in a minor salivary gland: report of a case

Reichart, Peter ; Kalz, Steffen ; Rabel, Annette ; Bornstein, Michael

In: Oral and Maxillofacial Surgery, 2010, vol. 14, no. 1, p. 59-62

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    Summary
    Background: Carcinoma ex pleomorphic adenoma is exceedingly rare in minor salivary glands of the oral cavity. We present a case of carcinoma ex pleomorphic adenoma (CEPA) of the buccal mucosa in a 47-year-old Turkish patient. The buccal mass was of a size of 1.5cm located in the left cheek. Pleomorphic adenoma was the tentative diagnosis. Methods: The tumor was removed under local anesthesia. Histopathologic evaluation revealed a preexisting pleomorphic adenoma associated with adenoid tumor component with tubulo-cystic and papillary or pseudopapillary structures; CEPA was diagnosed. Capsular integrity was incomplete with infiltration by islands of metaplastic/dysplastic epithelium. Results: Secondary surgery of the site was performed. No tumor tissue could be detected in the resection specimen. The patient is free of recurrence since 9months