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Reproducibility of straylight measurement by C-Quant for assessment of retinal straylight using the compensation comparison method

Guber, Ivo ; Bachmann, Lucas ; Guber, Josef ; Bochmann, Frank ; Lange, Alex ; Thiel, Michael

In: Graefe's Archive for Clinical and Experimental Ophthalmology, 2011, vol. 249, no. 9, p. 1367-1371

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    Titel
    • Reproducibility of straylight measurement by C-Quant for assessment of retinal straylight using the compensation comparison method
    Autor
    • Guber, Ivo. Jules-Gonin Eye Hospital, University of Lausanne, Avenue de France 15, 1000 Lausanne 7, Vaud, Switzerland
    • Bachmann, Lucas. medignition Inc. Research Consultants, Zug, Switzerland
    • Guber, Josef. Eye Clinic, Cantonal Hospital of Lucerne, Lucerne, Switzerland
    • Bochmann, Frank. Eye Clinic, Cantonal Hospital of Lucerne, Lucerne, Switzerland
    • Lange, Alex. Department of Ophthalmology, Toronto Western Hospital, Toronto, Ontario, Canada
    • Thiel, Michael. Eye Clinic, Cantonal Hospital of Lucerne, Lucerne, Switzerland
    Dokumententyp
    • Postprint
    Sprache
    • Englisch
    Veröffentlicht in
    • Graefe's Archive for Clinical and Experimental Ophthalmology, 2011, vol. 249, no. 9, p. 1367-1371. Springer-Verlag
    Andere elektronische Ausgabe
    OAI-PMH-ID
    • oai:doc.rero.ch:319656
    Summary
    Background: Straylight gives the appearance of a veil of light thrown over a person's retinal image when there is a strong light source present. We examined the reproducibility of the measurements by C-Quant, and assessed its correlation to characteristics of the eye and subjects' age. Participants and Methods: Five repeated straylight measurements were taken using the dominant eye of 45 healthy subjects (age 21-59) with a BCVA of 20/20: 14 emmetropic, 16 myopic, eight hyperopic and seven with astigmatism. We assessed the extent of reproducibility of straylight measures using the intraclass correlation coefficient. Results: The mean straylight value of all measurements was 1.01 (SD 0.23, median 0.97, interquartile range 0.85-1.1). Per 10years of age, straylight increased in average by 0.10 (95%CI 0.04 to 0.16, p < 0.01]. We found no independent association of refraction (range −5.25 dpt to +2 dpt) on straylight values (0.001; 95%CI −0.022 to 0.024, p = 0.92). Compared to emmetropic subjects, myopia reduced straylight (−.011; −0.024 to 0.02, p = 0.11), whereas higher straylight values (0.09; −0.01 to 0.20, p = 0.09) were observed in subjects with blue irises as compared to dark-colored irises when correcting for age. The intraclass correlation coefficient (ICC) of repeated measurements was 0.83 (95%CI 0.76 to 0.90). Conclusions: Our study showed that straylight measurements with the C-Quant had a high reproducibility, i.e. a lack of large intra-observer variability, making it appropriate to be applied in long-term follow-up studies assessing the long-term effect of surgical procedures on the quality of vision