Premiere use of Integra™ artificial skin to close an extensive fetal skin defect during open in utero repair of myelomeningocele
Meuli, Martin ; Meuli-Simmen, Claudia ; Flake, Alan ; Zimmermann, Roland ; Ochsenbein, Nicole ; Scheer, Ianina ; Mazzone, Luca ; Moehrlen, Ueli
In: Pediatric Surgery International, 2013, vol. 29, no. 12, p. 1321-1326
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- Background: There are fetuses demonstrating very large myelomeningocele lesion which can not be covered with autochothonous skin. Material and Methods: We use Integra™ artifical skin for intrauterine coverage of the back lesion. A reverse latissimus dorsi flap was used postnataly to reinforce the repair site. Conclusion: Integra™ appears to be a suitable coverage for large soft tissue defects in utero. Moreover, a postnatal reverse latissimus dorsi flap appears to markedly strengthen tissue coverage over a spinal cord rescued in utero