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Is there a correlation between venlafaxine therapy during pregnancy and a higher incidence of necrotizing enterocolitis?

Treichel, Markus ; Schwendener Scholl, Katharina ; Kessler, Ulf ; Joeris, Alexander ; Nelle, Mathias

In: World Journal of Pediatrics, 2009, vol. 5, no. 1, p. 65-67

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    Title
    • Is there a correlation between venlafaxine therapy during pregnancy and a higher incidence of necrotizing enterocolitis?
    Author
    • Treichel, Markus. Department of Neonatology, Children's Hospital, University of Berne, Berne, Switzerland
    • Schwendener Scholl, Katharina. Department of Neonatology, Children's Hospital, University of Berne, Berne, Switzerland
    • Kessler, Ulf. Department of Surgical Pediatrics, Children's Hospital, University of Berne, Berne, Switzerland
    • Joeris, Alexander. Department of Surgical Pediatrics, Children's Hospital, University of Berne, Berne, Switzerland
    • Nelle, Mathias. Department of Neonatology, Children's Hospital, University of Berne, Berne, Switzerland
    Document Type
    • Postprint
    OAI-PMH Identifier
    • oai:doc.rero.ch:319232
    Summary
    Background: Novel antidepressant drugs are increasingly used by women of child bearing age. However, potentially harmful effects on fetus and newborn remain unknown. Methods: Case report and literature review. Results: We present preterm twins whose mother was treated with venlafaxine, a nonselective serotonin reuptake inhibitor, throughout pregnancy until delivery. The twins developed neonatal necrotizing enterocolitis. Conclusion: The question whether there might be a correlation between maternal serotonin reuptake inhibitor therapy and neonatal necrotizing enterocolitis is discussed