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Relevance of somatostatin receptors and other peptide receptors in pathology

Reubi, Jean

In: Endocrine Pathology, 1997, vol. 8, no. 1, p. 11-20

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    Title
    • Relevance of somatostatin receptors and other peptide receptors in pathology
    Author
    • Reubi, Jean. Division of Cell Biology and Experimental Cancer Research, Institute of Pathology, University of Berne, Murtenstrasse 31, CH-3010, BERNE, (Switzerland)
    Document Type
    • Postprint
    Language
    • English
    Published in
    • Endocrine Pathology, 1997, vol. 8, no. 1, p. 11-20. Humana Press
    Other Version
    OAI-PMH Identifier
    • oai:doc.rero.ch:318872
    Summary
    Receptors for regulatory peptides can be overexpressed by several diseases, in particular by neoplasms. This review summarizes the current status of knowledge in this field, on the basis of in vitro receptor studies and with emphasis on receptors for somatostatin as well as for substance P (SP), vasoactive intestinal polypeptide (VIP), and cholecystokinin. It evaluates the existing and potential clinical implications of the findings for diagnosis and therapy and discusses the role of the pathologist in this context