Image-guided multipolar radiofrequency ablation of liver tumours: initial clinical results
Terraz, Sylvain ; Constantin, Christophe ; Majno, Pietro ; Spahr, Laurent ; Mentha, Gilles ; Becker, Christoph
In: European Radiology, 2007, vol. 17, no. 9, p. 2253-2261
Ajouter à la liste personnelle- Summary
- The local effectiveness and clinical usefulness of multipolar radiofrequency (RF) ablation of liver tumours was evaluated. Sixty-eight image-guided RF sessions were performed using a multipolar device with bipolar electrodes in 53 patients. There were 45 hepatocellular carcinomas (HCC) and 42 metastases with a diameter ≤3cm (n = 55), 3.1-5cm (n = 29) and >5cm (n = 3); 26 nodules were within 5mm from large vessels. Local effectiveness and complications were evaluated after RF procedures. Mean follow-up was 17 ± 10months. Recurrence and survival rates were analysed by the Kaplan-Meier method. The primary and secondary technical effectiveness rate was 82% and 95%, respectively. The major and minor complication rate was 2.9%, respectively. The local tumour progression at 1- and 2-years was 5% and 9% for HCC nodules and 17% and 31% for metastases, respectively; four of 26 nodules (15%) close to vessels showed local progression. The survival at 1year and 2years was 97% and 90% for HCC and 84% and 68% for metastases, respectively. Multipolar RF technique creates ablation zones of adequate size and tailored shape and is effective to treat most liver tumours, including those close to major hepatic vessels