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Echinococcus granulosus strain typing in Bulgaria: the G1 genotype is predominant in intermediate and definitive wild hosts

Breyer, Isabel ; Georgieva, Dimitrina ; Kurdova, Rossitza ; Gottstein, Bruno

In: Parasitology Research, 2004, vol. 93, no. 2, p. 127-130

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    Titre
    • Echinococcus granulosus strain typing in Bulgaria: the G1 genotype is predominant in intermediate and definitive wild hosts
    Auteur
    • Breyer, Isabel. Institute of Parasitology, University of Berne, Länggass-Strasse 122, 3012, Berne, Switzerland
    • Georgieva, Dimitrina. Veterinary Faculty, Thracian University, Stara Zagora, Bulgaria
    • Kurdova, Rossitza. Department of Parasitology and Tropical Medicine, National Center of Infectious and Parasitic Diseases, 26 Yanko Sakazov Blvd., 1504, Sofia, Bulgaria
    • Gottstein, Bruno. Institute of Parasitology, University of Berne, Länggass-Strasse 122, 3012, Berne, Switzerland
    Type de document
    • Postprint
    Classification
    • Biologie, Sciences de la vie
    Identifiant OAI-PMH
    • oai:doc.rero.ch:317829
    Summary
    Addressing the genetic variability in Echinococcus granulosus is epidemiologically important, as strain characteristics may influence the local transmission patterns of zoonotic cystic echinococcosis. To classify the genotype(s) present in intermediate (pig, cattle and sheep) and definitive (jackal and wolf) hosts in Bulgaria, a DNA-based approach was used to assess parasite protoscoleces or strobiles. Genes corresponding to coding and non-coding regions of the nuclear and mitochondrial genome (ND-1, HBX, Act II, AgB-1) were amplified by PCR and subsequently sequenced. The sequences resolved were all found to be identical to those published for the common sheep strain of E. granulosus, indicating that the G1 genotype is predominant in Bulgaria. One microvariant for ND-1 was found in the pig isolates; however no epidemiological significance was attributed to this finding