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Molecular profiles of gastroenteropancreatic endocrine tumors

Perren, Aurel ; Anlauf, Martin ; Komminoth, Paul

In: Virchows Archiv, 2007, vol. 451, p. 39-46

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    Titre
    • Molecular profiles of gastroenteropancreatic endocrine tumors
    Auteur
    • Perren, Aurel. Department of Pathology, University Hospital Zürich, Zurich, Switzerland
    • Anlauf, Martin. Department of Pathology, University of Kiel, Kiel, Germany
    • Komminoth, Paul. Institute of Pathology, Stadtspital Triemli, Zürich, Switzerland
    Type de document
    • Postprint
    Identifiant OAI-PMH
    • oai:doc.rero.ch:310972
    Summary
    Neuroendocrine tumors of the gastroenteropancreatic system are defined by their endocrine phenotype and share many histopathological and clinical features. However, the fact that the hormone production of tumors depends on their site of origin, that the tumors differ in their biology, and that the association with familial syndromes is nonrandom suggests heterogeneity. It is therefore conceivable that the gastroenteropancreatic neuroendocrine tumors also differ in their molecular profile. This review summarizes and discusses the available data in this field