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The hysteroscopic view of infertility: the mid-secretory endometrium and treatment success towards pregnancy

Santi, A. ; Felser, R. ; Bersinger, N. ; Wunder, D. ; McKinnon, B. ; Mueller, M.

In: Gynecological Surgery, 2012, vol. 9, no. 2, p. 147-150

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    Titre
    • The hysteroscopic view of infertility: the mid-secretory endometrium and treatment success towards pregnancy
    Auteur
    • Santi, A.. Department of Obstetrics and Gynaecology, Inselspital, University of Berne, DKF Murtenstrasse 35, CH-3010, Berne, Switzerland
    • Felser, R.. Department of Obstetrics and Gynaecology, Inselspital, University of Berne, DKF Murtenstrasse 35, CH-3010, Berne, Switzerland
    • Bersinger, N.. Department of Obstetrics and Gynaecology, Inselspital, University of Berne, DKF Murtenstrasse 35, CH-3010, Berne, Switzerland
    • Wunder, D.. Department of Obstetrics and Gynaecology, Inselspital, University of Berne, DKF Murtenstrasse 35, CH-3010, Berne, Switzerland
    • McKinnon, B.. Department of Clinical Research, University of Berne, Berne, Switzerland
    • Mueller, M.. Department of Obstetrics and Gynaecology, Inselspital, University of Berne, DKF Murtenstrasse 35, CH-3010, Berne, Switzerland
    Type de document
    • Postprint
    Identifiant OAI-PMH
    • oai:doc.rero.ch:309753
    Summary
    The purpose of this study was the analysis of a correlation, in infertile patients, between the quality of the endometrium based on its vascularisation and the chances of conception. Hysteroscopy was carried out to determine the quality of the endometrial surface using the Sakumoto-Masamoto classification ("good” vs. "poor” endometrium) in the secretory phase of the menstrual cycle. The results were set in relation to the outcome of the subsequent infertility treatment, i.e. the establishment of a pregnancy within the study period (4years). In 108 (67%) of the 162 followed-up patients, the endometrium was endoscopically classified as "good”, while in 54 (33%) the result was "poor”. The overall pregnancy rate was 37% (60 patients); 47 of all pregnancies (78%) occurred in women with a "good” endometrium while 13 (22%) had a "poor” classification. This positive association between the establishment of a pregnancy in the follow-up and a "good" classification of the endometrial vasculature in the group with a "good" endometrium was significant (P = 0.0165, Fisher's exact test). This study confirms the usefulness of endometrial evaluation by hysteroscopy as a diagnostic instrument for providing a prognosis of the chance for the patients to become pregnant