β-Glucan Antigenemia Assay for the Diagnosis of Invasive Fungal Infections in Patients With Hematological Malignancies: A Systematic Review and Meta-Analysis of Cohort Studies From the Third European Conference on Infections in Leukemia (ECIL-3)

Lamoth, Frédéric ; Cruciani, Mario ; Mengoli, Carlo ; Castagnola, Elio ; Lortholary, Olivier ; Richardson, Malcolm ; Marchetti, Oscar

In: Clinical Infectious Diseases, 2012, vol. 54, no. 5, p. 633-643

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    Summary
    This Third European Conference on Infections in Leukemia meta-analysis of high-quality hemato-oncological cohort studies shows that 2 consecutive positive 1,3-β-D-glucan assays have high specificity and both positive and negative predictive values but low sensitivity for diagnosis of invasive fungal infection