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In vitro activity of commercial probiotic Lactobacillus strains against uropathogenic Escherichia coli

Delley, Michèle ; Bruttin, Anne ; Richard, Michel ; Affolter, Michael ; Rezzonico, Enea ; Brück, Wolfram M. ; Fanning, Séamus

In: FEMS Microbiology Letters, 2015, vol. 362, no. 13, p. -

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    Titre
    • In vitro activity of commercial probiotic Lactobacillus strains against uropathogenic Escherichia coli
    Auteur
    • Delley, Michèle. Nestec Ltd, Nestlé Research Center, PO Box 44, CH-1000 Lausanne 26, Switzerland
    • Bruttin, Anne. Nestec Ltd, Nestlé Research Center, PO Box 44, CH-1000 Lausanne 26, Switzerland
    • Richard, Michel. Nestec Ltd, Nestlé Research Center, PO Box 44, CH-1000 Lausanne 26, Switzerland
    • Affolter, Michael. Nestec Ltd, Nestlé Research Center, PO Box 44, CH-1000 Lausanne 26, Switzerland
    • Rezzonico, Enea. Nestec Ltd, Nestlé Research Center, PO Box 44, CH-1000 Lausanne 26, Switzerland
    • Brück, Wolfram M.. Nestec Ltd, Nestlé Research Center, PO Box 44, CH-1000 Lausanne 26, Switzerland
    • Fanning, Séamus
    Type de document
    • Postprint
    Langue
    • Anglais
    Publié dans
    • FEMS Microbiology Letters, 2015, vol. 362, p. 13. Oxford University Press
    Autre version électronique
    Identifiant OAI-PMH
    • oai:doc.rero.ch:304421
    Summary
    Urinary tract infection (UTI) is one of the most prevalent infections in humans. In ≥80% of cases, the etiologic agents are strains of uropathogenic Escherichia coli (UPEC), which commonly reside in the gastrointestinal tract. Lactobacilli have been shown to prevent UTI reoccurrence by restoring the urogenital microbiota when administered vaginally or orally. The goal of this study was to determine if commercial probiotic Lactobacillus spp. reduce or clear UPEC in vitro. Results show that it is likely that lactobacilli may, in addition to restoring a healthy urogenital microbiota through acidification of their environment, also displace adhering UPEC and cause a reduction of infection