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Procalcitonin to Guide Initiation and Duration of Antibiotic Treatment in Acute Respiratory Infections: An Individual Patient Data Meta-Analysis

Schuetz, Philipp ; Briel, Matthias ; Christ-Crain, Mirjam ; Stolz, Daiana ; Bouadma, Lila ; Wolff, Michel ; Luyt, Charles-Edouard ; Chastre, Jean ; Tubach, Florence ; Kristoffersen, Kristina B. ; Wei, Long ; Burkhardt, Olaf ; Welte, Tobias ; Schroeder, Stefan ; Nobre, Vandack ; Tamm, Michael ; Bhatnagar, Neera ; Bucher, Heiner C. ; Mueller, Beat

In: Clinical Infectious Diseases, 2012, vol. 55, no. 5, p. 651-662

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    Titre
    • Procalcitonin to Guide Initiation and Duration of Antibiotic Treatment in Acute Respiratory Infections: An Individual Patient Data Meta-Analysis
    Auteur
    • Schuetz, Philipp. Department of Emergency Medicine, Beth Israel Deaconess Medical Center, and Harvard School of Public Health, Boston, Massachusetts
    • Briel, Matthias. Basel Institute for Clinical Epidemiology and Biostatistics
    • Christ-Crain, Mirjam. Division of Endocrinology, Diabetology and Clinical Nutrition
    • Stolz, Daiana. Clinic of Pneumology and Pulmonary Cell Research, University Hospital Basel
    • Bouadma, Lila. Service de Réanimation Médicale, Université Paris 7-Denis-Diderot, Hôpital Bichat-Claude-Bernard, Assistance Publique-Hôpitaux de Paris (AP-HP)
    • Wolff, Michel. Service de Réanimation Médicale, Université Paris 7-Denis-Diderot, Hôpital Bichat-Claude-Bernard, Assistance Publique-Hôpitaux de Paris (AP-HP)
    • Luyt, Charles-Edouard. Service de Réanimation Médicale, EA3964, Université Paris 6-Pierre-et-Marie-Curie, Hôpital Pitié-Salpêtrière, AP-HP
    • Chastre, Jean. Service de Réanimation Médicale, EA3964, Université Paris 6-Pierre-et-Marie-Curie, Hôpital Pitié-Salpêtrière, AP-HP
    • Tubach, Florence. Département d'Epidémiologie Biostatistique et Recherche Clinique, AP-HP, Hôpital Bichat
    • Kristoffersen, Kristina B.. Department of Infectious Diseases, Aarhus University Hospital, Denmark
    • Wei, Long. Department of Emergency Medicine, Shanghai Fifth People's Hospital, China
    • Burkhardt, Olaf. Medizinische Hochschule Hannover, Department of Pulmonary Medicine, Hannover
    • Welte, Tobias. Medizinische Hochschule Hannover, Department of Pulmonary Medicine, Hannover
    • Schroeder, Stefan. Department of Anesthesiology and Intensive Care Medicine, Krankenhaus Dueren, Germany
    • Nobre, Vandack. Intensive Care, University Hospitals of Geneva
    • Tamm, Michael. Clinic of Pneumology and Pulmonary Cell Research, University Hospital Basel
    • Bhatnagar, Neera. Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Canada
    • Bucher, Heiner C.. Basel Institute for Clinical Epidemiology and Biostatistics
    • Mueller, Beat. Medical University Department of the Medical Faculty of the University of Basel, Kantonsspital Aarau, Switzerland
    Type de document
    • Postprint
    Langue
    • Inglese
    Publié dans
    • Clinical Infectious Diseases, 2012, vol. 55, no. 5, p. 651-662. Oxford University Press
    Autre version électronique
    Classification
    • Santé
    Identifiant OAI-PMH
    • oai:doc.rero.ch:303469
    Summary
    This individual patient data meta-analysis of clinical trials investigating procalcitonin algorithms for antibiotic decision making found no increased risk of death or setting-specific treatment failure but did find significantly lower antibiotic exposure across different acute respiratory infections and clinical settings