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Use of remifentanil in a patient with chronic hepatic failure

Dumont, L. ; Picard, V. ; Marti, R A. ; Tassonyi, E.

In: British journal of anaesthesia, 1998, vol. 81, no. 2, p. 265-267

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    Titre
    • Use of remifentanil in a patient with chronic hepatic failure
    Auteur
    • Dumont, L.. Department of Anaesthesiology, Pharmacology and Surgical Intensive Care, Geneva University Hospital, Switzerland.
    • Picard, V.. Department of Anaesthesiology, Pharmacology and Surgical Intensive Care, Geneva University Hospital, Switzerland.
    • Marti, R A.. Department of Anaesthesiology, Pharmacology and Surgical Intensive Care, Geneva University Hospital, Switzerland.
    • Tassonyi, E.. Department of Anaesthesiology, Pharmacology and Surgical Intensive Care, Geneva University Hospital, Switzerland.
    Type de document
    • Postprint
    Langue
    • Anglais
    Publié dans
    • British journal of anaesthesia, 1998, vol. 81, no. 2, p. 265-267
    Autre version électronique
    Identifiant OAI-PMH
    • oai:doc.rero.ch:303083
    Summary
    We describe a 73-yr-old woman anaesthetized for a laminectomy. She suffered from hepatic failure with mild encephalopathy complicated by several exacerbations associated with sedative and opioid therapy. The challenge for anaesthesia management was to provide adequate analgesia and avoid causing hepatic encephalopathy during and after the surgery. We used remifentanil to provide intraoperative and postoperative analgesia, because it has a short duration of action and does not require hepatic metabolism. We closely monitored the respiratory and the neurological status throughout the administration and conclude that remifentanil can provide perioperative analgesia in patients at risk of developing hepatic encephalopathy