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Measurement of serum haptoglobin as an indicator of the efficacy of malaria intervention trials

Sisay, F. ; Byass, P. ; Snow, R.W. ; Greenwood, B.M. ; Perrin, L.H. ; Yerly, S.

In: Transactions of The Royal Society of Tropical Medicine and Hygiene, 1992, vol. 86, no. 1, p. 14-16

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    Titel
    • Measurement of serum haptoglobin as an indicator of the efficacy of malaria intervention trials
    Autor
    • Sisay, F.. Medical Research Council Laboratories, Fajara, Banjul, The Gambia
    • Byass, P.. Medical Research Council Laboratories, Fajara, Banjul, The Gambia
    • Snow, R.W.. Medical Research Council Laboratories, Fajara, Banjul, The Gambia
    • Greenwood, B.M.. Medical Research Council Laboratories, Fajara, Banjul, The Gambia
    • Perrin, L.H.. Central Laboratory of Virology, Division of Infectious Diseases, Cantonal University Hospital of Geneva, Geneva, Switzerland
    • Yerly, S.. Central Laboratory of Virology, Division of Infectious Diseases, Cantonal University Hospital of Geneva, Geneva, Switzerland
    Dokumententyp
    • Postprint
    Sprache
    • Englisch
    Veröffentlicht in
    • Transactions of The Royal Society of Tropical Medicine and Hygiene, 1992, vol. 86, no. 1, p. 14-16. Royal Society of Tropical Medicine and Hygiene
    Andere elektronische Ausgabe
    Klassifikation
    • Gesundheit
    OAI-PMH-ID
    • oai:doc.rero.ch:300841
    Summary
    Serum haptoglobin levels were measured by an enzyme-linked immunosorbent assay in Gambian children who participated in 3 malaria intervention trials with untreated or impregnated bed nets. In one study, in which a significant effect on clinical malaria was observed, the mean serum haptoglobin level was significantly higher in the intervention than in the control group. In the other 2 studies, in which no significant protection was observed, mean haptoglobin levels were similar in intervention and control groups. Measurement of serum haptoglobin may provide a useful indirect measure of the effectiveness of malaria control programmes