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FLOTAC: A promising technique for detecting helminth eggs in human faeces

Knopp, Stefanie ; Glinz, Dominik ; Rinaldi, Laura ; Mohammed, Khalfan A. ; N'Goran, Eliézer K. ; Stothard, J. Russell ; Marti, Hanspeter ; Cringoli, Giuseppe ; Rollinson, David ; Utzinger, Jürg

In: Transactions of The Royal Society of Tropical Medicine and Hygiene, 2009, vol. 103, no. 12, p. 1190-1194

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    Title
    • FLOTAC: A promising technique for detecting helminth eggs in human faeces
    Author
    • Knopp, Stefanie. Department of Public Health and Epidemiology, Swiss Tropical Institute, P.O. Box, CH-4002 Basel, Switzerland
    • Glinz, Dominik. Department of Public Health and Epidemiology, Swiss Tropical Institute, P.O. Box, CH-4002 Basel, Switzerland
    • Rinaldi, Laura. Department of Pathology and Animal Health, CREMOPAR Regione Campania, University of Naples ‘Federico II', Via della Veterinaria 1, 80137 Naples, Italy
    • Mohammed, Khalfan A.. Helminth Control Laboratory Unguja, Ministry of Health and Social Welfare, P.O. Box 236, Mianzini, Zanzibar, Tanzania
    • N'Goran, Eliézer K.. Centre Suisse de Recherches Scientifiques, 01 BP 1303, Abidjan 01, Côte d'Ivoire
    • Stothard, J. Russell. Wolfson Wellcome Biomedical Laboratories, Biomedical Parasitology Division, Department of Zoology, Natural History Museum, Cromwell Road, London SW7 5BD, UK
    • Marti, Hanspeter. Department of Medical and Diagnostic Services, Swiss Tropical Institute, P.O. Box, CH-4002 Basel, Switzerland
    • Cringoli, Giuseppe. Department of Pathology and Animal Health, CREMOPAR Regione Campania, University of Naples ‘Federico II', Via della Veterinaria 1, 80137 Naples, Italy
    • Rollinson, David. Wolfson Wellcome Biomedical Laboratories, Biomedical Parasitology Division, Department of Zoology, Natural History Museum, Cromwell Road, London SW7 5BD, UK
    • Utzinger, Jürg. Department of Public Health and Epidemiology, Swiss Tropical Institute, P.O. Box, CH-4002 Basel, Switzerland
    Document Type
    • Postprint
    Language
    • English
    Published in
    • Transactions of The Royal Society of Tropical Medicine and Hygiene, 2009, vol. 103, no. 12, p. 1190-1194. Royal Society of Tropical Medicine and Hygiene
    Other Version
    OAI-PMH Identifier
    • oai:doc.rero.ch:299865
    Summary
    There is a tendency to neglect diagnostic issues in the era of ‘preventive chemotherapy' in human helminthiases. However, accurate diagnosis cannot be overemphasized for adequate patient management and monitoring of community-based control programmes. Implicit is a diagnostic dilemma: the more effective interventions are in reducing helminth egg excretion, the less sensitive direct parasitological tests become. Here, experiences gained thus far with the FLOTAC technique for diagnosing common soil-transmitted helminth infections are summarized. A single FLOTAC has higher sensitivity than multiple Kato-Katz thick smears in detecting low-intensity infections. Further validation of the FLOTAC technique in different epidemiological settings is warranted, including diagnosis of intestinal schistosomiasis and food-borne trematodiases