The status of PD-L1 and tumor-infiltrating immune cells predict resistance and poor prognosis in BRAFi-treated melanoma patients harboring mutant BRAFV600
Massi, D. ; Brusa, D. ; Merelli, B. ; Falcone, C. ; Xue, G. ; Carobbio, A. ; Nassini, R. ; Baroni, G. ; Tamborini, E. ; Cattaneo, L. ; Audrito, V. ; Deaglio, S. ; Mandalà, M.
In: Annals of Oncology, 2015, vol. 26, no. 9, p. 1980-1987
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- In the present study, we have provided clinical evidence of the predictive and prognostic relevance of tumoral PD-L1 expression and density of immune cell infiltration in BRAFV600-mutated metastatic melanoma patients treated with BRAF inhibitors