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Physical activity and energy expenditure in rheumatoid arthritis patients and matched controls

Henchoz, Yves ; Bastardot, François ; Guessous, Idris ; Theler, Jean-Marc ; Dudler, Jean ; Vollenweider, Peter ; So, Alexander

In: Rheumatology, 2012, vol. 51, no. 8, p. 1500-1507

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    Title
    • Physical activity and energy expenditure in rheumatoid arthritis patients and matched controls
    Author
    • Henchoz, Yves. Service of Rheumatology, Department of Musculoskeletal Medicine, Department of Medicine, Lausanne University Hospital, Lausanne, Unit of Population Epidemiology, Division of Primary Care Medicine, Department of Community Medicine, Primary Care and Emergency Medicine, Geneva University Hospitals, Geneva, Community Prevention Unit, Institute of Social and Preventive Medicine, Department of Community Medicine and Health, Lausanne University Hospital, Lausanne and Department of Rheumatology, HFR Fribourg - Hôpital Cantonal, Fribourg, Switzerland.
    • Bastardot, François. Service of Rheumatology, Department of Musculoskeletal Medicine, Department of Medicine, Lausanne University Hospital, Lausanne, Unit of Population Epidemiology, Division of Primary Care Medicine, Department of Community Medicine, Primary Care and Emergency Medicine, Geneva University Hospitals, Geneva, Community Prevention Unit, Institute of Social and Preventive Medicine, Department of Community Medicine and Health, Lausanne University Hospital, Lausanne and Department of Rheumatology, HFR Fribourg - Hôpital Cantonal, Fribourg, Switzerland.
    • Guessous, Idris. Service of Rheumatology, Department of Musculoskeletal Medicine, Department of Medicine, Lausanne University Hospital, Lausanne, Unit of Population Epidemiology, Division of Primary Care Medicine, Department of Community Medicine, Primary Care and Emergency Medicine, Geneva University Hospitals, Geneva, Community Prevention Unit, Institute of Social and Preventive Medicine, Department of Community Medicine and Health, Lausanne University Hospital, Lausanne and Department of Rheumatology, HFR Fribourg - Hôpital Cantonal, Fribourg, Switzerland.
    • Theler, Jean-Marc. Service of Rheumatology, Department of Musculoskeletal Medicine, Department of Medicine, Lausanne University Hospital, Lausanne, Unit of Population Epidemiology, Division of Primary Care Medicine, Department of Community Medicine, Primary Care and Emergency Medicine, Geneva University Hospitals, Geneva, Community Prevention Unit, Institute of Social and Preventive Medicine, Department of Community Medicine and Health, Lausanne University Hospital, Lausanne and Department of Rheumatology, HFR Fribourg - Hôpital Cantonal, Fribourg, Switzerland.
    • Dudler, Jean. Service of Rheumatology, Department of Musculoskeletal Medicine, Department of Medicine, Lausanne University Hospital, Lausanne, Unit of Population Epidemiology, Division of Primary Care Medicine, Department of Community Medicine, Primary Care and Emergency Medicine, Geneva University Hospitals, Geneva, Community Prevention Unit, Institute of Social and Preventive Medicine, Department of Community Medicine and Health, Lausanne University Hospital, Lausanne and Department of Rheumatology, HFR Fribourg - Hôpital Cantonal, Fribourg, Switzerland.
    • Vollenweider, Peter. Service of Rheumatology, Department of Musculoskeletal Medicine, Department of Medicine, Lausanne University Hospital, Lausanne, Unit of Population Epidemiology, Division of Primary Care Medicine, Department of Community Medicine, Primary Care and Emergency Medicine, Geneva University Hospitals, Geneva, Community Prevention Unit, Institute of Social and Preventive Medicine, Department of Community Medicine and Health, Lausanne University Hospital, Lausanne and Department of Rheumatology, HFR Fribourg - Hôpital Cantonal, Fribourg, Switzerland.
    • So, Alexander. Service of Rheumatology, Department of Musculoskeletal Medicine, Department of Medicine, Lausanne University Hospital, Lausanne, Unit of Population Epidemiology, Division of Primary Care Medicine, Department of Community Medicine, Primary Care and Emergency Medicine, Geneva University Hospitals, Geneva, Community Prevention Unit, Institute of Social and Preventive Medicine, Department of Community Medicine and Health, Lausanne University Hospital, Lausanne and Department of Rheumatology, HFR Fribourg - Hôpital Cantonal, Fribourg, Switzerland.
    Document Type
    • Postprint
    OAI-PMH Identifier
    • oai:doc.rero.ch:295328
    Summary
    Objectives. To compare daily energy expenditure between RA patients and matched controls, and to explore the relationship between daily energy expenditure or sedentariness and disease-related scores. Methods. One hundred and ten patients with RA and 440 age- and sex-matched controls were included in this study. Energy expenditure was assessed using the validated physical activity (PA) frequency questionnaire. Disease-related scores included disease activity (DAS-28), functional status (HAQ), pain visual analogue scale (VAS) and fatigue VAS. Total energy expenditure (TEE) and the amount of energy spent in low- (TEE-low), moderate- (TEE-mod) and high-intensity (TEE-high) PAs were calculated. Sedentariness was defined as expending <10% of TEE in TEE-mod or TEE-high activities. Between-group comparisons were computed using conditional logistic regression. The effect of disease-related scores on TEE was investigated using linear regression. Results. TEE was significantly lower for RA patients compared with controls [2392 kcal/day (95% CI 2295, 2490) and 2494 kcal/day (2446, 2543), respectively, P = 0.003]. A significant difference was found between groups in TEE-mod (P = 0.015), but not TEE-low (P = 0.242) and TEE-high (P = 0.146). All disease-related scores were significantly poorer in sedentary compared with active patients. TEE was inversely associated with age (P < 0.001), DAS-28 (P = 0.032) and fatigue VAS (P = 0.029), but not with HAQ and pain VAS. Conclusion. Daily energy expenditure is significantly lower in RA patients compared with matched controls, mainly due to less moderate-intensity PAs performed. Disease activity and fatigue are important contributing factors. These points need to be addressed if promoting PA in RA patients is a health goal. Trial registration. ClinicalTrials.gov, http://clinicaltrials.gov, NCT01228812