Fulltext

Experimental Bacterial Endocarditis After Dental Extractions in Rats with Periodontitis

Overholser, C. Daniel ; Moreillon, Philippe ; Glauser, Michel P.

In: Journal of Infectious Diseases, 1987, vol. 155, no. 1, p. 107-112

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    Titel
    • Experimental Bacterial Endocarditis After Dental Extractions in Rats with Periodontitis
    Autor
    • Overholser, C. Daniel. Department of Oral Diagnosis, Baltimore College of Dental Surgery, Dental School, Baltimore, Maryland, Lausanne, Switzerland
    • Moreillon, Philippe. Department of Oral Diagnosis, Baltimore College of Dental Surgery, Dental School, Baltimore, Maryland, Lausanne, Switzerland
    • Glauser, Michel P.. Department of Oral Diagnosis, Baltimore College of Dental Surgery, Dental School, Baltimore, Maryland, Lausanne, Switzerland
    Dokumententyp
    • Postprint
    Sprache
    • Englisch
    Veröffentlicht in
    • Journal of Infectious Diseases, 1987, vol. 155, no. 1, p. 107-112. The University of Chicago Press
    Andere elektronische Ausgabe
    Klassifikation
    • Gesundheit
    OAI-PMH-ID
    • oai:doc.rero.ch:294311
    Summary
    The development of bacterial endocarditis was analyzed after dental extractions in rats with or without periodontal disease. Periodontal disease was produced in rats by tying silk ligatures around the two maxillary first molars and placing the animals on a high sucrose diet for 14 weeks. Sterile aortic valve vegetations were produced by means of a transaortic catheter, and 24 hr later the maxillary first molars were extracted. The animals were killed 72 hr after the extractions. In rats with periodontal disease, extractions resulted in a 48% (14 of 29) incidence of bacterial endocarditis, most cases of which were due to Streptococcus spp. (one was caused by Staphylococcus aureus). In contrast, when the teeth with a healthy periodontium were extracted, only 6% (one of 15) of the rats developed endocarditis. When catheters were placed in anim, tis with periodontal disease but no extractions were performed, no endocarditis occurred