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Assessment of Cytomegalovirus-Specific Cell-Mediated Immunity for the Prediction of Cytomegalovirus Disease in High-Risk Solid-Organ Transplant Recipients: A Multicenter Cohort Study

Manuel, Oriol ; Husain, Shahid ; Kumar, Deepali ; Zayas, Carlos ; Mawhorter, Steve ; Levi, Marilyn E. ; Kalpoe, Jayant ; Lisboa, Luiz ; Ely, Leticia ; Kaul, Daniel R. ; Schwartz, Brian S. ; Morris, Michele I. ; Ison, Michael G. ; Yen-Lieberman, Belinda ; Sebastian, Anthony ; Assi, Maha ; Humar, Atul

In: Clinical Infectious Diseases, 2013, vol. 56, no. 6, p. 817-824

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    Title
    • Assessment of Cytomegalovirus-Specific Cell-Mediated Immunity for the Prediction of Cytomegalovirus Disease in High-Risk Solid-Organ Transplant Recipients: A Multicenter Cohort Study
    Author
    • Manuel, Oriol. Infectious Diseases Service and Transplantation Center, University Hospital and University of Lausanne, Switzerland
    • Husain, Shahid. Department of Medicine, Division of Infectious Diseases, University Health Network, University of Toronto
    • Kumar, Deepali. Alberta Transplant Institute, University of Alberta, Edmonton, Canada
    • Zayas, Carlos. Transplant Services, Piedmont Hospital, Atlanta, Georgia
    • Mawhorter, Steve. Department of Infectious Diseases, Cleveland Clinic, Ohio
    • Levi, Marilyn E.. Division of Infectious Diseases, University of Colorado, Aurora
    • Kalpoe, Jayant. Department of Medical Microbiology, Leiden University Medical Center, The Netherlands
    • Lisboa, Luiz. Alberta Transplant Institute, University of Alberta, Edmonton, Canada
    • Ely, Leticia. Alberta Transplant Institute, University of Alberta, Edmonton, Canada
    • Kaul, Daniel R.. Department of Internal Medicine, Division of Infectious Disease, University of Michigan Medical School, Ann Arbor
    • Schwartz, Brian S.. Division of Infectious Diseases, University of California, San Francisco
    • Morris, Michele I.. Division of Infectious Diseases, University of Miami Miller School of Medicine, Florida
    • Ison, Michael G.. Divisions of Infectious Diseases and Organ Transplantation, Northwestern University Feinberg School of Medicine, Chicago, Illinois
    • Yen-Lieberman, Belinda. Section of Immunopathology, Pathology and Laboratory Medicine Institute, Cleveland Clinic, Ohio
    • Sebastian, Anthony. Abdominal Transplant Surgery Division, Oklahoma Transplant Center, University of Oklahoma Health Sciences Center, Oklahoma City
    • Assi, Maha. Department of Infectious Disease, University of Kansas School of Medicine, Wichita
    • Humar, Atul. Alberta Transplant Institute, University of Alberta, Edmonton, Canada
    Document Type
    • Postprint
    Language
    • English
    Published in
    • Clinical Infectious Diseases, 2013, vol. 56, no. 6, p. 817-824. Oxford University Press
    Other Version
    OAI-PMH Identifier
    • oai:doc.rero.ch:292845
    Summary
    In high-risk solid-organ transplant recipients receiving antiviral prophylaxis, the measurement of specific cell-mediated immunity using the Quantiferon assay appropriately stratified the individual risk of developing subsequent cytomegalovirus disease