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Neonatal Hemolytic Uremic Syndrome After Mother-to-Child Transmission of a Low-Pathogenic stx2b Harboring Shiga Toxin-Producing Escherichia coli

Stritt, Andrea ; Tschumi, Sibylle ; Kottanattu, Lisa ; Bucher, Barbara S. ; Steinmann, Markus ; von Steiger, Niklaus ; Stephan, Roger ; Hächler, Herbert ; Simonetti, Giacomo D.

In: Clinical Infectious Diseases, 2013, vol. 56, no. 1, p. 114-116

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    Title
    • Neonatal Hemolytic Uremic Syndrome After Mother-to-Child Transmission of a Low-Pathogenic stx2b Harboring Shiga Toxin-Producing Escherichia coli
    Author
    • Stritt, Andrea. University Children's Hospital, Inselspital and University of Bern, Switzerland
    • Tschumi, Sibylle. University Children's Hospital, Inselspital and University of Bern, Switzerland
    • Kottanattu, Lisa. University Children's Hospital, Inselspital and University of Bern, Switzerland
    • Bucher, Barbara S.. University Children's Hospital, Inselspital and University of Bern, Switzerland
    • Steinmann, Markus. University Children's Hospital, Inselspital and University of Bern, Switzerland
    • von Steiger, Niklaus. Institute for Infectious Diseases, University of Bern
    • Stephan, Roger. Institute for Food Safety and Hygiene, National Centre for Enteropathogenic Bacteria and Listeria, University of Zürich, Switzerland
    • Hächler, Herbert. Institute for Food Safety and Hygiene, National Centre for Enteropathogenic Bacteria and Listeria, University of Zürich, Switzerland
    • Simonetti, Giacomo D.. University Children's Hospital, Inselspital and University of Bern, Switzerland
    Document Type
    • Postprint
    Language
    • English
    Published in
    • Clinical Infectious Diseases, 2013, vol. 56, no. 1, p. 114-116. Oxford University Press
    Other Version
    OAI-PMH Identifier
    • oai:doc.rero.ch:292811
    Summary
    This case describes evidence for a Shiga toxin-producing Escherichia coli (STEC) O146:H28 infection leading to hemolytic uremic syndrome in a neonate. STEC O146:H28 was linked hitherto with asymptomatic carriage in humans. Based on strain characteristics and genotyping data, the mother is a healthy carrier who transmitted the STEC during delivery. STEC strains belonging to the low-pathogenic STEC group must also be considered in the workup of neonatal hemolytic uremic syndrome